化合物K可抑制由白细胞介素-17A处理和紫外线B照射诱导的表皮衰老。
Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation.
作者信息
Kim A Young, Jung Ji-Yong, Kim Donghyun, Cho Jeong Hun, Hong Yong Deog, Kim Hyoung-June, Cho Si-Young
机构信息
Research and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
出版信息
J Ginseng Res. 2025 May;49(3):326-330. doi: 10.1016/j.jgr.2025.03.004. Epub 2025 Mar 21.
Abstract
We evaluated the anti-accelerated epidermal skin aging effects of compound K (CK) on keratinocytes using IL-17A and ultraviolet B. CK restored epidermal functions and reduced the induction of pro-inflammatory cytokines by inhibiting NF-κB and p38 MAPK activation. CK plays a significant role in controlling accelerated epidermal skin aging.
摘要
我们使用白细胞介素-17A和紫外线B评估了化合物K（CK）对角质形成细胞的抗表皮加速衰老作用。CK通过抑制核因子κB（NF-κB）和p38丝裂原活化蛋白激酶（p38 MAPK）的激活来恢复表皮功能并减少促炎细胞因子的诱导。CK在控制表皮加速衰老中发挥着重要作用。
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