Emral Ahmet Cihangir
Department of General Surgery, Atılım University Faculty of Medicine, Ankara, Türkiye.
Front Surg. 2025 May 16;12:1565209. doi: 10.3389/fsurg.2025.1565209. eCollection 2025.
Ectopic liver tissue (ELT) is a rare embryological anomaly most commonly found in the abdominal region, particularly on the gallbladder. It is generally asymptomatic and is often discovered incidentally during surgery or autopsy. Although histologically similar to the main liver, ELT should be excised due to the potential risk of malignancy.
This study presents a case of incidental ELT discovered during elective cholecystectomy in a 34-year-old female patient. Preoperative imaging revealed multiple gallstones, and during laparoscopic exploration, an ectopic liver tissue lesion was found on the gallbladder fundus. The lesion, measuring 10 × 5 mm, was excised with the gallbladder and sent for pathological examination, which showed no malignancy.
The rarity and asymptomatic nature of ELT make it difficult to diagnose preoperatively, but its association with malignant transformation warrants careful management. In cases of suspected malignancy, further surgical approaches such as extended surgical margins and regional lymph node dissection should be considered.
This case underscores the importance of early detection and excision of ectopic liver tissue due to its potential for malignant transformation.
异位肝组织（ELT）是一种罕见的胚胎学异常，最常见于腹部区域，尤其是在胆囊上。它通常无症状，常在手术或尸检时偶然发现。尽管在组织学上与主要肝脏相似，但由于存在恶性转化的潜在风险，ELT应予以切除。
本研究报告了一例在一名34岁女性患者择期胆囊切除术期间偶然发现的ELT病例。术前影像学检查发现多发胆结石，在腹腔镜探查过程中，在胆囊底部发现一个异位肝组织病变。该病变大小为10×5毫米，与胆囊一并切除并送去做病理检查，结果显示无恶性病变。
ELT的罕见性和无症状性使其术前难以诊断，但其与恶性转化的关联值得谨慎处理。在怀疑有恶性病变的情况下，应考虑进一步的手术方法，如扩大手术切缘和区域淋巴结清扫。
该病例强调了由于异位肝组织有恶性转化的可能性，早期发现并切除的重要性。
