Weiss B D, Watkins S
J Fam Pract. 1985 Oct;21(4):285-7.
One hundred ten consecutive patients undergoing 35-cm flexible sigmoidoscopy were enrolled in a study to compare the efficacy of one vs two enemas (Fleet's) in achieving adequate bowel preparation. Fifty-five patients received two enemas administered one and three hours before sigmoidoscopy. The other 55 subjects received one enema given one hour before the procedure. Bowel preparation was considered inadequate if sigmoidoscopy was terminated prematurely because fecal material obscured visualization through the sigmoidoscope. Inadequate bowel preparation occurred in 12.9 percent of subjects who received one enema and in 20.0 percent of those who received two enemas (chi 2 = 0.97, P = .36). There was no difference between the groups in depth of penetration of the sigmoidoscope or duration (in minutes) of the examination. It is concluded that either one or two enemas are equally effective in preparing patients for sigmoidoscopy. Patient acceptance of sigmoidoscopy could be enhanced by using one enema instead of two with no decrease in adequacy of bowel preparation.
110名连续接受35厘米可弯曲乙状结肠镜检查的患者参与了一项研究，以比较一次灌肠（弗利特灌肠剂）与两次灌肠在实现充分肠道准备方面的效果。55名患者在乙状结肠镜检查前1小时和3小时各接受一次灌肠。另外55名受试者在检查前1小时接受一次灌肠。如果因粪便遮挡乙状结肠镜视野而提前终止乙状结肠镜检查，则认为肠道准备不充分。接受一次灌肠的受试者中12.9%肠道准备不充分，接受两次灌肠的受试者中20.0%肠道准备不充分（卡方检验χ2 = 0.97，P = 0.36）。两组在乙状结肠镜的插入深度或检查持续时间（分钟）方面没有差异。结论是，一次灌肠或两次灌肠在为患者进行乙状结肠镜检查准备方面同样有效。使用一次灌肠而非两次灌肠可提高患者对乙状结肠镜检查的接受度，且不会降低肠道准备的充分性。
