低丙种球蛋白血症中的铁状态。
Iron status in hypogammaglobulinaemia.
作者信息
Atrah H I
出版信息
J R Soc Med. 1985 Oct;78(10):838-41. doi: 10.1177/014107688507801009.
Iron, transferrin and ferritin were measured in serum samples from 16 patients with primary hypogammaglobulinaemia. Transferrin saturation was low in 12 patients (75%) and serum ferritin was low in 9 patients (56.25%). Both parameters were low, confirming the state of iron deficiency, in 6 patients (37.5%). These figures are highly significant (P less than 0.01) when compared with the prevalence of iron deficiency in the general population. Eight patients were maintained on intravenous immunoglobulin infusions and the rest on intramuscular immunoglobulin injections, their mean serum IgG being 4.4 g/l and 2.6 g/l respectively. There was no difference in the prevalence of iron deficiency between the two groups.
对16例原发性低丙种球蛋白血症患者的血清样本进行了铁、转铁蛋白和铁蛋白检测。12例患者（75%）的转铁蛋白饱和度较低，9例患者（56.25%）的血清铁蛋白较低。6例患者（37.5%）的这两个参数均较低，证实存在缺铁状态。与普通人群中铁缺乏的患病率相比，这些数据具有高度显著性（P小于0.01）。8例患者接受静脉注射免疫球蛋白治疗，其余患者接受肌肉注射免疫球蛋白治疗，他们的平均血清IgG分别为4.4 g/l和2.6 g/l。两组之间缺铁的患病率没有差异。
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