Gill Sana Munir, Hassan Aamna, Qureshi Pir Abdul Ahad Aziz, Bashir Humayun
Shaukat Khanum Memorial Cancer Hospital and Research Centre, Clinic of Nuclear Medicine, Lahore, Pakistan.
Landspítali -The National University Hospital, Clinic of Nuclear Medicine, Reykjavik, Iceland.
Mol Imaging Radionucl Ther. 2025 Jun 3;34(2):156-158. doi: 10.4274/mirt.galenos.2024.26879.
Neurolymphomatosis (NL) is a rare clinical condition characterized by the infiltration of malignant lymphocytes into the cranial or peripheral nerves, nerve roots, or plexus. Diagnosis can be clinically challenging due to its variable presentation. It usually occurs in B cell lymphoma; however, a few cases of extranodal killer/T cell lymphoma. Most cases present at a secondary site in patients with primary site in remission. Fluorine fluorodeoxyglucose positron emission tomography/computed tomography plays an important role in the early detection of NL, resulting in timely treatment. We present a case of a 24-year-old male with nasal natural killer T cell lymphoma who initially responded to treatment but relapsed with NL based on clinical and radiological findings.
神经淋巴瘤（NL）是一种罕见的临床病症，其特征为恶性淋巴细胞浸润至颅神经或周围神经、神经根或神经丛。由于其表现多样，临床诊断具有挑战性。它通常发生于B细胞淋巴瘤；不过，也有少数结外杀伤/ T细胞淋巴瘤病例。大多数病例出现在原发部位缓解的患者的继发部位。氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在NL的早期检测中发挥着重要作用，从而实现及时治疗。我们报告一例24岁男性鼻型自然杀伤T细胞淋巴瘤患者，该患者最初对治疗有反应，但根据临床和影像学检查结果复发为神经淋巴瘤。
