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全球疾病负担研究中未经治疗龋齿不平等现象的结构决定因素

Structural determinants of inequalities in untreated dental caries in the Global Burden of Disease Study.

作者信息

do Amaral Junior Orlando Luiz, Braccini Fagundes Maria Laura, Hugo Fernando Neves, Kassebaum Nicholas J, do Amaral Giordani Jessye Melgarejo

机构信息

Postgraduate Program in Dental Sciences, Federal University of Santa Maria, Santa Maria, Brazil.

College of Dentistry, Department of Epidemiology and Health Promotion, New York University, New York, New York, United States of America.

出版信息

PLoS One. 2025 Jun 3;20(6):e0325138. doi: 10.1371/journal.pone.0325138. eCollection 2025.

Abstract

INTRODUCTION

Untreated dental caries remains a significant global public health challenge, disproportionately affecting vulnerable populations and highlighting inequalities in health systems worldwide. Examining its distribution across diverse contexts is essential for guiding targeted interventions, informing public policies, and allocating resources more effectively. This study aims to provide a comprehensive global assessment of the distribution of untreated dental caries in 204 countries and territories, spanning the years 2000, 2010, and 2019, by dimensions of structural determinants of health.

METHODS

This study employs an ecological design. This analysis describes the incidence, prevalence and years lived with disability (YLDs) due to untreated dental caries in permanent and deciduous teeth by structural determinants of health (dimensions of governance, macroeconomic policy, social policy, public policies and culture/societal values), for 204 countries and territories. Estimates of untreated caries in deciduous teeth by structural determinants were reported for children under 5 years of age, whereas estimates in permanent teeth were described for adolescents and adults aged between 15 and 49 years. Estimates were retrieved from the Global Health Data Exchange.

RESULTS

There was a gradient of inequality between countries in terms of prevalence, YLDs, and the incidence of overt untreated caries. Countries that had better structural indicators had lower mean prevalence of untreated caries in primary teeth. In the permanent dentition, between-countries inequalities were not identified. Additionally, the mean prevalence was stable from 2010 to 2019.

CONCLUSIONS

This study revealed possible cross-country inequalities in the burden of untreated caries in deciduous teeth that persisted over one decade. More developed countries experienced less disease burden. These findings show the need for targeted interventions to address the uneven burden of untreated dental caries worldwide.

CLINICAL SIGNIFICANCE

This study underscores the need for targeted global health policies to reduce untreated dental caries, especially in countries with lower structural health determinants, highlighting cross-country inequalities in disease burden and the importance of addressing these disparities in both primary and permanent dentition.

摘要

引言

未经治疗的龋齿仍然是一项重大的全球公共卫生挑战,对弱势群体的影响尤为严重,凸显了全球卫生系统中的不平等现象。研究其在不同环境中的分布情况对于指导针对性干预措施、为公共政策提供信息以及更有效地分配资源至关重要。本研究旨在通过健康的结构性决定因素维度,对2000年、2010年和2019年期间204个国家和地区未经治疗的龋齿分布情况进行全面的全球评估。

方法

本研究采用生态设计。该分析按健康的结构性决定因素(治理、宏观经济政策、社会政策、公共政策和文化/社会价值观维度)描述了204个国家和地区恒牙和乳牙中因未经治疗的龋齿导致的发病率、患病率和伤残调整生命年(YLDs)。报告了5岁以下儿童乳牙中按结构性决定因素划分的未经治疗龋齿的估计数,而描述了15至49岁青少年和成年人恒牙中的估计数。估计数从全球卫生数据交换中心获取。

结果

各国在患病率、YLDs以及明显未经治疗龋齿的发病率方面存在不平等梯度。结构性指标较好的国家乳牙中未经治疗龋齿的平均患病率较低。在恒牙列中,未发现国家间的不平等现象。此外,2010年至2019年期间平均患病率保持稳定。

结论

本研究揭示了乳牙中未经治疗龋齿负担在十年间可能存在的跨国不平等现象。较发达国家的疾病负担较轻。这些发现表明需要采取针对性干预措施来应对全球未经治疗龋齿负担不均的问题。

临床意义

本研究强调需要制定针对性的全球卫生政策以减少未经治疗的龋齿,特别是在结构性健康决定因素较低的国家,凸显了疾病负担的跨国不平等以及解决乳牙和恒牙列中这些差异的重要性。

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