Chen Beibei, Liang Hairui, Yang Lei, Zhou Xueting, Cai Zhencun
Department of Orthopedics Surgery, Central Hospital affiliated to Shenyang Medical College, 5 Nanqi West Road, Shenyang, 110075, Liaoning, China.
Pharmacy Department, The People's Hospital of Liaoning Province, No. 33 Wenyi Road, Shenhe District, Shenyang City, 110000, Liaoning Province, China.
Sci Rep. 2025 Jun 4;15(1):19514. doi: 10.1038/s41598-025-04586-0.
In patients with Crowe III developmental dysplasia of the hip (DDH), surgery presents challenges such as severe bone defects and inadequate acetabular cup coverage. This study compares the clinical efficacy of 3D-printed personalized Augments prostheses with conventional femoral head reshaping and structural bone grafting in total hip arthroplasty (THA) for patients with Crowe III DDH. A retrospective analysis was conducted on 52 Crowe III patients. The 3D group (26 cases) used 3D printing technology combined with computer simulation to design personalized Augments prostheses. Preoperative models were printed to simulate the surgical procedure, and high-porosity porous structured Augments prostheses and acetabular cup layers were printed using titanium alloy powder. The non-3D group (26 cases) underwent traditional femoral head reshaping and structural bone grafting. The study compared the differences in lower limb length, the horizontal and vertical distances of the hip joint rotation center from the teardrop line, acetabular cup abduction angle, acetabular cup coverage, operation time, intraoperative blood loss, postoperative time to mobilization, time to hospital discharge, Harris hip scores during follow-up, and complications between the two groups. In the 3D group compared to the non-3D group, intraoperative blood loss (261.92 ± 14.70 vs. 313.85 ± 20.02 ml, P < 0.05), time to mobilization (1.27 ± 0.45 vs. 4.85 ± 1.05 days, P < 0.05), and time to discharge (2.77 ± 0.65 vs. 5.85 ± 0.92 days, P < 0.05) were significantly lower, as was the limb length discrepancy on the first postoperative day (0.25 ± 0.21 cm vs. 0.48 ± 0.28 cm, P < 0.05). The acetabular cup coverage rates on the first postoperative day and at 3 months postoperatively (1 ± 0.00 vs. 0.93 ± 0.07; 1 ± 0.00 vs. 0.83 ± 0.11, P < 0.05) were significantly higher in the 3D group. The Harris hip scores at 3, 6, and 12 months postoperatively were also higher in the 3D group than in the non-3D group, with statistically significant differences (P < 0.05). The application of 3D-printed personalized augment prostheses in total hip arthroplasty provides a relatively feasible treatment option for patients with Crowe type III DDH. This approach contributes to personalized treatment and shows potential in improving surgical accuracy and certain treatment outcomes.
在Crowe III型发育性髋关节发育不良(DDH)患者中,手术面临着诸如严重骨缺损和髋臼杯覆盖不足等挑战。本研究比较了3D打印个性化增强假体与传统股骨头重塑及结构性植骨在Crowe III型DDH患者全髋关节置换术(THA)中的临床疗效。对52例Crowe III型患者进行了回顾性分析。3D组(26例)采用3D打印技术结合计算机模拟设计个性化增强假体。打印术前模型以模拟手术过程,并使用钛合金粉末打印高孔隙率多孔结构增强假体和髋臼杯层。非3D组(26例)接受传统股骨头重塑及结构性植骨。该研究比较了两组在下肢长度、髋关节旋转中心距泪滴线的水平和垂直距离、髋臼杯外展角度、髋臼杯覆盖率、手术时间、术中出血量、术后活动时间、出院时间、随访期间的Harris髋关节评分以及并发症方面的差异。与非3D组相比,3D组术中出血量(261.92±14.70 vs. 313.85±20.02 ml,P<0.05)、活动时间(1.27±0.45 vs. 4.85±1.05天,P<0.05)和出院时间(2.77±0.65 vs. 5.85±0.92天,P<0.05)显著更低,术后第一天的肢体长度差异也更小(0.25±0.21 cm vs. 0.48±0.28 cm,P<0.05)。3D组术后第一天和术后3个月的髋臼杯覆盖率显著更高(1±0.00 vs. 0.93±0.07;1±0.00 vs. 0.83±0.11,P<0.05)。3D组术后3个月、6个月和12个月的Harris髋关节评分也高于非3D组,差异有统计学意义(P<0.05)。3D打印个性化增强假体在全髋关节置换术中的应用为Crowe III型DDH患者提供了一种相对可行的治疗选择。这种方法有助于个性化治疗,并在提高手术准确性和某些治疗效果方面显示出潜力。