Zhang Heng, Liu Yang, Dong Qirong, Guan Jianzhong, Zhou Jiansheng
Department of Orthopedics, the First Affiliated Hospital of Bengbu Medical College, Laboratory of Tissue and Transplant in Anhui Province, Bengbu Medical College, Bengbu City, Anhui Province.
Department of Orthopedics, the Second Affiliated Hospital of Soochow University, Suzhou City, Jiangsu Province, China.
Medicine (Baltimore). 2020 Oct 2;99(40):e22578. doi: 10.1097/MD.0000000000022578.
Exact restoration of the rotation center in total hip arthroplasty (THA) is technically challenging in patients with end-stage osteoarthritis due to developmental dysplasia of the hip (DDH), especially in the Crowe type II and III procedures. The technical difficulty is attributable to the complex acetabular changes. In this study, a novel 3-dimensional (3D) printed integral customized acetabular prosthesis for anatomical rotation restoration in THA for DDH Crowe type III was developed using patient-specific Computer-aided design and additive manufacturing (AM) methods.
A 69-year-old female patient had developed left hip joint pain and restricted movement for 40 years; the symptoms had increased in the past 5 months. Pain, limited motion of the left hip joint, and lower limb length discrepancy were noted during physical examination.
The patient was diagnosed with left hip end-stage osteoarthritis secondary to DDH (Crowe type III).
A 3D printed acetabulum model was manufactured and a simulated operation was performed to improve the accuracy of reconstruction of the rotation center and bone defect. A 3D printed titanium alloy integral customized acetabular prosthesis was designed according to the result of simulated operation. The integral customized prothesis was implanted subsequently via the posterolateral approach. Radiography of the pelvis and Harris score assessment were performed during the perioperative period as well as at the 6- and 12-month follow-up.
The 3D printed integral customized acetabular prosthesis matched precisely with the reamed acetabulum. The rotation center was restored and the bone defect was exactly reconstructed. There were no signs of prosthetic loosening at the 12-month follow-up. The Harris score gradually improved during the follow-up period.
Satisfactory results of hip rotation restoration and bone defect reconstruction could be achieved by using 3D printed integral customized acetabular prosthesis, which provides a promising way to reconstruct the acetabulum in patients with DDH anatomically and rapidly for THA.
对于因髋关节发育不良(DDH)导致终末期骨关节炎的患者,在全髋关节置换术(THA)中精确恢复旋转中心在技术上具有挑战性,尤其是在Crowe II型和III型手术中。技术难度归因于复杂的髋臼变化。在本研究中,使用患者特异性计算机辅助设计和增材制造(AM)方法,开发了一种新型三维(3D)打印整体定制髋臼假体,用于DDH Crowe III型THA中的解剖旋转恢复。
一名69岁女性患者左髋关节疼痛并活动受限40年;症状在过去5个月加重。体格检查发现左髋关节疼痛、活动受限及下肢长度不等。
患者被诊断为继发于DDH(Crowe III型)的左髋关节终末期骨关节炎。
制造3D打印髋臼模型并进行模拟手术,以提高旋转中心和骨缺损重建的准确性。根据模拟手术结果设计3D打印钛合金整体定制髋臼假体。随后通过后外侧入路植入整体定制假体。围手术期以及6个月和12个月随访时进行骨盆X线摄影和Harris评分评估。
3D打印整体定制髋臼假体与磨锉后的髋臼精确匹配。旋转中心得以恢复,骨缺损得到精确重建。12个月随访时无假体松动迹象。随访期间Harris评分逐渐改善。
使用3D打印整体定制髋臼假体可实现髋关节旋转恢复和骨缺损重建的满意结果,为DDH患者在THA中进行髋臼解剖学和快速重建提供了一种有前景的方法。