含荧光素牙膏对固定正畸矫治器患者牙菌斑的影响：一项随机临床试验。

Effect of fluorescein-containing toothpaste on dental plaque in patients with fixed orthodontic appliances: a randomized clinical trial.

作者信息

Omidkhoda Maryam, Charbgoo Masoumeh, Bagheri Hossein, Naghibi Nava, Eslami Neda

机构信息

Dental Materials Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Orthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

BMC Oral Health. 2025 Jun 3;25(1):895. doi: 10.1186/s12903-025-05977-5.

DOI:10.1186/s12903-025-05977-5

PMID:40462033

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12135612/

Abstract

BACKGROUND

The increased incidence of dental caries and periodontal disease is one of the greatest concerns of orthodontic patients. The present study aimed to assess the effect of fluorescein-containing toothpaste on removal of dental plaque in patients with fixed orthodontic appliances.

METHODS

We conducted a single-blind randomized controlled trial in 40 patients referred to orthodontic department of Mashhad dental school. All patients were over 12 years old with fixed orthodontic appliances. At the start of the study, proper tooth brushing was instructed to the patients. One month after regular brushing according to instructions, the patients were randomly assigned into two groups. Allocation concealment was operated via sealed packed envelope. The control group received regular toothpaste and continued brushing as before, while the intervention group received fluorescein-containing toothpaste and identified the location of the remaining plaque using the LED light. One month after oral hygiene instructions, the orthodontic plaque index (OPI) and gingival bleeding index (GBI) of patients were measured (T). Also, OPI and GBI were measured again after 1 month of using their received toothpastes (T).

RESULTS

There was not a significant difference between the two groups in terms of age and sex. Also, no significant difference was found in maxillary and mandibular OPI changes (T-T) between the two groups after 1 month. Similarly, the mean scores of GBI reduction were not significant between the two groups.

CONCLUSIONS

The fluorescein-containing toothpaste did not significantly reduce plaque and gingival bleeding compared to the control group after 1 month. Therefore, proper oral hygiene and patient education seem to be more important than plaque disclosing agents in reducing dental plaque around orthodontic appliances.

TRIAL REGISTRATION NUMBER

The study was registered at the Iranian Registry of Clinical Trials: IRCT20200509047355N1. (Registration date: 30.5.2020)

摘要

背景

龋齿和牙周疾病发病率的增加是正畸患者最担心的问题之一。本研究旨在评估含荧光素牙膏对固定正畸矫治器患者牙菌斑清除的效果。

方法

我们在40名转诊至马什哈德牙科学院正畸科的患者中进行了一项单盲随机对照试验。所有患者年龄均超过12岁，佩戴固定正畸矫治器。在研究开始时，指导患者正确刷牙。按照指示定期刷牙1个月后，将患者随机分为两组。通过密封包装的信封进行分配隐藏。对照组使用常规牙膏并继续像以前一样刷牙，而干预组使用含荧光素牙膏，并使用LED灯确定剩余牙菌斑的位置。在进行口腔卫生指导1个月后，测量患者的正畸牙菌斑指数（OPI）和牙龈出血指数（GBI）（T）。在使用所提供的牙膏1个月后，再次测量OPI和GBI（T）。