Lin Wulian, Wu Cuiling, Xu Guilin, Yi Gaocheng, Zhang Guanpo, Li Haitao, Zheng Jin, Li Dazhou, Wang Wen
Department of Gastroenterology, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, Fujian, China.
Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, China.
Front Immunol. 2025 May 20;16:1562853. doi: 10.3389/fimmu.2025.1562853. eCollection 2025.
This paper presents four cases of autoimmune gastritis coexisting with Helicobacter pylori- associated gastritis, all of which developed gastric tumors, with some cases exhibiting multiple histological origins. Through a narrative literature review, we explore the potential mechanisms and clinical implications of tumor development in this context. This report emphasizes the significance of recognizing synergistic mucosal injury in chronic gastritis management and highlights the need for future studies into combined pathogenesis.
本文介绍了4例自身免疫性胃炎合并幽门螺杆菌相关性胃炎的病例，所有病例均发生了胃肿瘤，部分病例呈现多种组织学起源。通过叙述性文献综述，我们探讨了在这种情况下肿瘤发生的潜在机制和临床意义。本报告强调了在慢性胃炎管理中认识协同性黏膜损伤的重要性，并突出了未来对联合发病机制进行研究的必要性。
