Ihara Clinic of Internal Medicine, Japan.
Department of Pathology, Shiga University of Medical Science, Japan.
Intern Med. 2023 Mar 15;62(6):855-863. doi: 10.2169/internalmedicine.0195-22. Epub 2022 Aug 10.
Autoimmune gastritis (AIG) typically exhibits the characteristics of type A gastritis and has been classified as a separate disease from type B gastritis that corresponds to Helicobacter pylori gastritis. However, many reports have suggested the involvement of H. pylori infection in the pathogenesis of AIG. In our two cases, the patients' previous gastritis exhibited a clear pattern in which H. pylori gastritis had progressed over many years, but ultimately transitioned to AIG with its spontaneous disappearance. These findings suggest that some cases of AIG might originate from long-standing H. pylori gastritis.
自身免疫性胃炎(AIG)通常表现为 A 型胃炎的特征,已被归类为与幽门螺杆菌胃炎相对应的 B 型胃炎的一种独立疾病。然而,许多报道表明,幽门螺杆菌感染参与了 AIG 的发病机制。在我们的两个病例中,患者之前的胃炎呈现出一种明确的模式,即多年来幽门螺杆菌胃炎逐渐进展,但最终自行消失,转变为 AIG。这些发现表明,一些 AIG 病例可能源自长期的幽门螺杆菌胃炎。