IgG2和抗原浓度对牛布鲁氏菌病补体结合试验中前带现象的影响。
The effects of IgG2 and of antigen concentration on prozoning in the complement fixation test for bovine brucellosis.
作者信息
McNaught D J, Chappel R J, Allan G S, Bourke J A, Rogerson B A
出版信息
Res Vet Sci. 1977 Mar;22(2):194-7.
PMID:404679
Abstract
Addition of Brucella-specific IgG2 to solutions of Brucella-specific IgG1 initially induced prozoning and at higher concentrations prevented all reaction in the complement fixation test (CFT) for bovine brucellosis. Some infected cattle may be diagnosed as brucellosis-free due to a high ratio of specific IgG2 to IgG1. Increasing the concentration of antigen in the CFT reduced the tendency to prozone.
摘要
在布鲁氏菌特异性IgG1溶液中添加布鲁氏菌特异性IgG2，最初会诱导前带现象，且在较高浓度时会抑制牛布鲁氏菌病补体结合试验（CFT）中的所有反应。一些感染牛可能因特异性IgG2与IgG1的比例较高而被诊断为无布鲁氏菌病。在CFT中增加抗原浓度可降低前带倾向。
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