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孕期基于药房的艾滋病毒预防服务中女性想要什么?为肯尼亚西部的一项离散选择实验确定属性和水平。

What do women want in pharmacy-based HIV prevention services during pregnancy? Developing attributes and levels for a discrete choice experiment in Western Kenya.

作者信息

Mugambi Melissa Latigo, Dollah Annabell, Ouda Rosebel, Oyugi Nancy, Odhiambo Ben O, Marwa Mary M, Nyakina Judith, Kinuthia John, Weiner Bryan J, John-Stewart Grace, Barnabas Ruanne Vanessa, Hauber Brett

机构信息

Department of Global Health, University of Washington, Seattle, USA.

UW-Kenya, Nairobi, Kenya.

出版信息

AIDS Res Ther. 2025 Jun 4;22(1):58. doi: 10.1186/s12981-025-00752-6.

Abstract

BACKGROUND

The delivery of HIV prevention services (e.g., HIV testing, pre-exposure prophylaxis (PrEP) initiation and refills, and STI testing) in community pharmacies could address clinic barriers faced by pregnant women such as extended travel and wait times. We conducted a qualitative study in Western Kenya to select and prioritize attributes and levels for a discrete choice experiment (DCE) to design pharmacy-based HIV prevention services for pregnant women.

METHODS

We began by identifying a comprehensive list of attributes and levels relevant to women considering HIV prevention during pregnancy. This list was informed by recommended HIV prevention interventions for pregnant women, our objective to design services for pharmacy settings, and attributes identified in the literature as important for other populations when choosing HIV and pharmacy-based services. From March to November 2022, we recruited participants using stratified purposeful sampling and collected qualitative data through seven focus group discussions with women, four with health providers, and eight individual interviews with technical experts. Interviews were audio-recorded, translated, transcribed, and summarized in debrief reports. We conducted debriefing meetings and analyzed these reports to identify and refine the essential attributes that would influence decisions to access HIV prevention services from a pharmacy during pregnancy.

RESULTS

We initially identified twelve potential attributes that were evaluated during the focus groups. Five attributes were eliminated based on ranking exercises with women and health providers. Additional attributes suggested during the focus groups were ranked low by participants or not mentioned frequently enough and, therefore, not included. We finalized and refined levels for each attribute using insights from the literature, participant feedback, and design considerations. The study identified seven attributes: service location, type of HIV test, STI testing availability, partner HIV testing availability, PrEP availability, service access methods (e.g., appointment versus walk-ins), and service fee.

CONCLUSIONS

This study was the first step in data collection toward defining attributes and levels for a DCE survey and successfully identified seven preliminary attributes and levels. Pre-testing and pilot testing activities further explored the feasibility and understanding of the attributes and levels.

摘要

背景

在社区药房提供艾滋病毒预防服务(例如,艾滋病毒检测、暴露前预防(PrEP)起始用药及补充用药,以及性传播感染检测)可以解决孕妇面临的诊所障碍,如路途遥远和等待时间长等问题。我们在肯尼亚西部开展了一项定性研究,以选择离散选择实验(DCE)的属性和水平并确定其优先级,从而为孕妇设计基于药房的艾滋病毒预防服务。

方法

我们首先确定了一份与孕期考虑艾滋病毒预防的女性相关的全面属性和水平清单。这份清单参考了针对孕妇的推荐艾滋病毒预防干预措施、我们为药房环境设计服务的目标,以及文献中确定的在选择艾滋病毒和基于药房的服务时对其他人群重要的属性。2022年3月至11月,我们采用分层目的抽样法招募参与者,并通过与女性进行的七次焦点小组讨论、与医疗服务提供者进行的四次讨论以及与技术专家进行的八次个人访谈收集定性数据。访谈进行了录音、翻译、转录,并在汇报报告中进行了总结。我们召开了汇报会议并分析这些报告,以确定和完善会影响孕期从药房获取艾滋病毒预防服务决策的基本属性。

结果

我们最初确定了十二个在焦点小组中进行评估的潜在属性。根据与女性和医疗服务提供者的排序练习,五个属性被剔除。焦点小组期间提出的其他属性被参与者排在较低位置或提及频率不够高,因此未被纳入。我们利用文献见解、参与者反馈和设计考量,最终确定并完善了每个属性的水平。该研究确定了七个属性:服务地点、艾滋病毒检测类型、性传播感染检测的可及性、伴侣艾滋病毒检测的可及性、暴露前预防的可及性、服务获取方式(例如,预约与无需预约)以及服务费用。

结论

本研究是为离散选择实验调查定义属性和水平的数据收集的第一步,并成功确定了七个初步属性和水平。预测试和试点测试活动进一步探讨了这些属性和水平的可行性及理解情况。

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