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新冠疫情对患有严重精神疾病的成年人的心理和社会心理功能、生活质量及康复的影响:来自荷兰纵向队列研究的结果

The impact of the COVID-19 pandemic on mental and psychosocial functioning, quality of life, and recovery in adults with severe mental illness: Findings from Dutch longitudinal cohorts.

作者信息

van Rijn Lotte, Swildens Wilma E, Metz Margot J, Everaerd Daphne, Polderman Tinca, Cahn Wiepke, Schellekens Arnt F A, Zijlmans Josjan, Zinkstok Janneke R

机构信息

Department of Psychiatry, Brain Center, https://ror.org/0575yy874University Medical Center Utrecht, Utrecht, The Netherlands.

Department of Psychiatry, https://ror.org/05wg1m734Radboud University Medical Center, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The Netherlands.

出版信息

Eur Psychiatry. 2025 Jun 5;68(1):e74. doi: 10.1192/j.eurpsy.2025.10039.

Abstract

BACKGROUND

The coronavirus disease 2019 (COVID-19) pandemic has impacted global mental health, with individuals with severe mental illness (SMI) being particularly vulnerable. Research on changes in psychiatric symptoms during this pandemic has yielded inconsistent results, often due to individual heterogeneity and a limited focus on broader outcomes such as psychosocial functioning, societal and personal recovery, and quality of life (QoL). Furthermore, long-term effects remain underexplored. This longitudinal cohort study aimed to assess the COVID-19 pandemic's impact on mental and psychosocial functioning, QoL, and recovery in individuals with SMI, and to explore individual and treatment characteristics associated with outcome changes.

METHODS

Two cohorts were included, involving adults (≥18 years) diagnosed with DSM-5 disorders and experiencing long-term impairments. Participants received care between January 1, 2018 and December 31, 2023. Outcomes included the Health of the Nation Outcome Scales, the Manchester Short Assessment of Quality of Life, and the Individual Recovery Outcomes Counter. Changes were analyzed across five pandemic periods using linear mixed models.

RESULTS

Improvements in mental and psychosocial functioning, QoL, and recovery were observed over time, regardless of the COVID-19 pandemic period. However, progress was slower during the COVID-19 pandemic compared to pre-pandemic levels. No individual or treatment characteristics were significantly linked to changes in outcomes.

CONCLUSION

The findings suggest that the COVID-19 pandemic had a minimal negative impact on individuals with SMI. This may be due to the marginal negative effects of the pandemic on this population, or the mitigating role of stabilizing factors within the current Dutch care models.

摘要

背景

2019年冠状病毒病(COVID-19)大流行对全球心理健康产生了影响,严重精神疾病(SMI)患者尤其脆弱。关于这一大流行期间精神症状变化的研究结果并不一致,这通常是由于个体异质性以及对社会心理功能、社会和个人康复以及生活质量(QoL)等更广泛结果的关注有限。此外,长期影响仍未得到充分探索。这项纵向队列研究旨在评估COVID-19大流行对SMI患者的心理和社会心理功能、QoL及康复的影响,并探索与结果变化相关的个体和治疗特征。

方法

纳入了两个队列,涉及被诊断患有DSM-5障碍并经历长期损伤的成年人(≥18岁)。参与者在2018年1月1日至2023年12月31日期间接受护理。结果指标包括国家健康结果量表、曼彻斯特生活质量简短评估量表和个人康复结果计数器。使用线性混合模型分析了五个大流行时期的变化情况。

结果

随着时间的推移,无论处于COVID-19大流行的哪个时期,心理和社会心理功能、QoL及康复均有改善。然而,与大流行前水平相比,COVID-19大流行期间进展较慢。没有个体或治疗特征与结果变化有显著关联。

结论

研究结果表明,COVID-19大流行对SMI患者的负面影响最小。这可能是由于大流行对该人群的负面影响较小,或者是当前荷兰护理模式中稳定因素的缓解作用。

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