Choi So Young, Kim Jieun, Song Eun Ho, Park Eunhye, Wu Jingrui, Yoo Juyeon, Nam Jwa-Min
Department of Chemistry, Seoul National University, Seoul, 08826, South Korea.
Small Methods. 2025 Jun 5:e2500448. doi: 10.1002/smtd.202500448.
Unlike the fixed formations of static gold nanostructures (AuNSs), reconfigurable AuNSs offer versatility when designing nanomaterials and biosensors because they can dynamically respond to external stimuli in a tunable manner. These dynamic systems enable in situ reaction monitoring and cyclic switching functions. An appropriate design of the architecture of the nanostructures is crucial because it dictates the operational principles of the system. This review explores the design and working principles of reconfigurable gold-based plasmonic nanostructures by modulating highly programmable DNA and through chemical and physical stimuli such as temperature, light, pH, and metal ions. Methods are discussed to control these factors and use them as actuation handles for affecting the reconfigurability of these structures. In addition, the utilization of these properties and functions in bio-applications and functional hybrid materials is illustrated, which demonstrates the practical applications of reconfigurable AuNSs in advanced materials science and biomedicine.
与静态金纳米结构（AuNSs）的固定结构不同，可重构AuNSs在设计纳米材料和生物传感器时具有多功能性，因为它们可以以可调方式动态响应外部刺激。这些动态系统能够实现原位反应监测和循环切换功能。纳米结构的架构设计得当至关重要，因为它决定了系统的运行原理。本综述通过调制高度可编程的DNA以及利用温度、光、pH值和金属离子等化学和物理刺激，探索了可重构金基等离子体纳米结构的设计和工作原理。文中讨论了控制这些因素并将其用作影响这些结构可重构性的驱动手段的方法。此外，还阐述了这些特性和功能在生物应用和功能性杂化材料中的利用情况，这展示了可重构AuNSs在先进材料科学和生物医学中的实际应用。
