圣保罗州一家四级医院治疗的系统性硬化症患者的流行病学概况。
EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH SYSTEMIC SCLEROSIS TREATED AT A QUATERNARY HOSPITAL IN THE STATE OF SÃO PAULO.
作者信息
Tenório Pedro Henrique de Magalhães, de Oliveira Rafaella Camilo, Portilho Pinto Ribeiro Matheus, Alves Queiroz Ramon, Marcatto de Abreu Marcos Felipe
机构信息
Universidade Estadual de Campinas (UNICAMP), Hospital de Clínicas, Campinas, Sao Paulo, SP, Brazil.
出版信息
Acta Ortop Bras. 2025 Jun 2;33(2):e287081. doi: 10.1590/1413-785220253302e287081. eCollection 2025.
OBJECTIVE
To report the profile of patients diagnosed with systemic sclerosis and monitored in a four-year hospital in São Paulo.
METHODS
Observational study with 51 patients, mostly composed of women. Descriptive statistics such as mean age, proportions (sex, ethnicity, form of the disease), and correlations between functional scores (HAQ, SHAQ, and Rodnan score) were extracted.
RESULTS
The average age found was 49.96 ± 12.01 years. The time since diagnosis was 11.19 ± 10.16 years. When separated by sex, 25% of men presented the limited form, while 65.9% of women presented the localized form. There was a statistically significant correlation (p-value<0.01) between the Rodnan score and the HAQ score, with a value of 0.36 (CI: 0.09-0.58), as well as with the SHAQ score (value of 0.33; CI: 0.05-0.55, p-value=0.01). When evaluating the correlation between the Rodnan score and the Cochin functional scale, there was a statistically significant correlation (p-value<0.01), with a value of 0.38 (0.12-0.58).
CONCLUSION
According to the literature, this study showed the highest prevalence in women, and the predominant form is limited.
目的
报告在圣保罗一家医院接受为期四年监测的系统性硬化症患者的概况。
方法
对51例患者进行观察性研究，大多数为女性。提取描述性统计数据，如平均年龄、比例（性别、种族、疾病类型）以及功能评分（健康评估问卷、系统性硬化症健康评估问卷和罗德南评分）之间的相关性。
结果
发现平均年龄为49.96±12.01岁。诊断后的时间为11.19±10.16年。按性别划分时，25%的男性表现为局限性形式，而65.9%的女性表现为局限性形式。罗德南评分与健康评估问卷评分之间存在统计学显著相关性（p值<0.01），值为0.36（置信区间：0.09 - 0.58），与系统性硬化症健康评估问卷评分也存在相关性（值为0.33；置信区间：0.05 - 0.55，p值 = 0.01）。在评估罗德南评分与科钦功能量表之间的相关性时，存在统计学显著相关性（p值<0.01），值为0.38（0.12 - 0.58）。
结论
根据文献，本研究显示女性患病率最高，且主要形式为局限性。
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