Sánchez-Sánchez Mario, Carrillo-Tripp Jimena, Aispuro-Hernández Emmanuel, Quintana-Obregón Eber Addí, Martínez-Téllez Miguel Ángel
Laboratorio de Fisiología Vegetal, Centro de Investigación en Alimentación y Desarrollo A.C., Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, 83304 Hermosillo, Sonora México.
Departamento de Microbiología, Centro de Investigación Científica y de Educación Superior de Ensenada, Carretera Ensenada-Tijuana No. 3918, Zona Playitas, 22860 Ensenada, Baja California México.
J Plant Pathol. 2023;105(1):83-94. doi: 10.1007/s42161-022-01287-9. Epub 2022 Dec 7.
The genus comprises a group of single-stranded RNA viruses that affect a wide variety of vegetables of economic importance. Tobamoviruses express a series of proteins that interact with the plant's cellular machinery, allowing viral infection; during incompatible interactions, active defense is mediated by host proteins encoded by resistance genes. The genes conferring viral resistance and tolerance in non-susceptible hosts have been studied for their ability to transfer desired resistance traits to different crops. The gene from spp., the repertoire of genes in spp., the locus from spp., and genes are the most studied genetic sequences for understanding resistance to tobamoviruses. Through classical plant breeding and genetic engineering techniques, it has been possible to introgress these resistance genes () into new species. However, new reports highlight the ability of tobamoviruses to overcome -mediated defense. One of the most notorious recent cases is the tomato brown rugose fruit virus (ToBRFV). The main characteristic of ToBRFV is its capacity to overcome the resistance mediated by the gene, resulting in a limited repertoire of options to combat the virus. To defeat emerging viruses, it is necessary to apply the knowledge from other tobamoviruses-host relationships and use new technologies such as genome-wide association studies (GWAS) to understand and associate the architecture of resistance genes present in the Solanaceae family for the benefit of plant breeding. Although new genomic tools such as CRISPR systems open the possibility of coping with viral diseases, there are no commercial ToBRFV-resistant tomato varieties. Hence, the world's leading seed suppliers compete to develop and bring these varieties to market.
The online version contains supplementary material available at 10.1007/s42161-022-01287-9.
该属包含一组单链RNA病毒，可感染多种具有经济重要性的蔬菜。烟草花叶病毒属病毒表达一系列与植物细胞机制相互作用的蛋白质，从而实现病毒感染；在不亲和相互作用中，主动防御由抗性基因编码的宿主蛋白介导。人们研究了非敏感宿主中赋予病毒抗性和耐受性的基因，以了解它们将所需抗性性状转移到不同作物的能力。来自番茄属物种的基因、辣椒属物种中基因的全部组成、烟草属物种的位点以及基因是研究最多的用于理解对烟草花叶病毒属病毒抗性的遗传序列。通过经典植物育种和基因工程技术，已能够将这些抗性基因导入新物种。然而，新的报告强调了烟草花叶病毒属病毒克服介导防御的能力。最近最臭名昭著的案例之一是番茄褐色皱纹果病毒（ToBRFV）。ToBRFV的主要特征是其能够克服由基因介导的抗性，导致对抗该病毒的选择有限。为了战胜新出现的病毒，有必要应用来自其他烟草花叶病毒属病毒与宿主关系的知识，并使用全基因组关联研究（GWAS）等新技术来理解和关联茄科植物中存在的抗性基因结构，以利于植物育种。尽管CRISPR系统等新的基因组工具为应对病毒病带来了可能性，但目前尚无商业化的抗ToBRFV番茄品种。因此，全球主要种子供应商竞相开发并将这些品种推向市场。
在线版本包含可在10.1007/s42161-022-01287-9获取的补充材料。
