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数字孪生技术在骨科创伤手术中的优势——探索不同的临床应用案例

Advantages of digital twin technology in orthopedic trauma Surgery - Exploring different clinical use cases.

作者信息

Andres Annchristin, Roland Michael, Wickert Kerstin, Diebels Stefan, Stöckl Johannes, Herrmann Stefan, Reinauer Frank, Leibinger Ralf, Pavlov Atanas, Schuppener Lutz, Schäfer Daniel, Histing Tina, Braun Benedikt J

机构信息

Saarland University, Applied Mechanics, Saarbrücken, Germany.

csi entwicklungstechnik GmbH, Neckarsulm, Germany.

出版信息

Sci Rep. 2025 Jun 6;15(1):19987. doi: 10.1038/s41598-025-04792-w.


DOI:10.1038/s41598-025-04792-w
PMID:40481259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12144170/
Abstract

Digital twin technology offers significant benefits for addressing fracture non-unions in orthopedic trauma surgery, particularly in cases requiring revision surgery. In this study, we developed a clinically applicable digital twin workflow that integrates patient-specific imaging, motion capture, musculoskeletal modeling, and finite element simulation. We applied this workflow to five real patient cases involving different anatomical sites and treatment strategies, including implant modification, augmentative fixation, and corrective osteotomy. Each case was virtually reconstructed to evaluate mechanical conditions before and after revision surgery. The results demonstrated that digital twins can predict improvements in implant stress distribution and fracture strain states, offering valuable insights for optimizing surgical decisions. This work highlights the feasibility of digital twins and their clinical value in supporting individualized revision strategies, laying the foundation for their broader use in trauma care. .

摘要

数字孪生技术在解决骨科创伤手术中的骨折不愈合问题方面具有显著优势,尤其是在需要翻修手术的病例中。在本研究中,我们开发了一种临床适用的数字孪生工作流程,该流程整合了患者特异性成像、运动捕捉、肌肉骨骼建模和有限元模拟。我们将此工作流程应用于五个涉及不同解剖部位和治疗策略的真实患者病例,包括植入物修改、增强固定和截骨矫正。每个病例都进行了虚拟重建,以评估翻修手术前后的力学状况。结果表明,数字孪生可以预测植入物应力分布和骨折应变状态的改善,为优化手术决策提供有价值的见解。这项工作突出了数字孪生的可行性及其在支持个性化翻修策略方面的临床价值,为其在创伤护理中的更广泛应用奠定了基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/cfcf487db5dd/41598_2025_4792_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/1c88099ebed0/41598_2025_4792_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/10b046705832/41598_2025_4792_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/3a62d1e43090/41598_2025_4792_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/7bf4601b75c9/41598_2025_4792_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/fd05f14cf543/41598_2025_4792_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/95589e50f5b4/41598_2025_4792_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/3cc3ca97cb14/41598_2025_4792_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/cfcf487db5dd/41598_2025_4792_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/1c88099ebed0/41598_2025_4792_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/10b046705832/41598_2025_4792_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/3a62d1e43090/41598_2025_4792_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/7bf4601b75c9/41598_2025_4792_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/fd05f14cf543/41598_2025_4792_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/95589e50f5b4/41598_2025_4792_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/3cc3ca97cb14/41598_2025_4792_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/12144170/cfcf487db5dd/41598_2025_4792_Fig8_HTML.jpg

相似文献

[1]
Advantages of digital twin technology in orthopedic trauma Surgery - Exploring different clinical use cases.

Sci Rep. 2025-6-6

[2]
Semi-automated finite element analyses of surgically treated acetabular fractures to investigate the biomechanical behaviour of patient-specific compared to conventional implants.

J Orthop Surg Res. 2024-9-5

[3]
Application of Digital Orthopedic Technology in Orthopedic Trauma.

Comput Math Methods Med. 2022

[4]
Development and validation of a digital twin of the human lower jaw under impact loading by using non-linear finite element analyses.

J Mech Behav Biomed Mater. 2023-12

[5]
Development of Digital Twins to Optimize Trauma Surgery and Postoperative Management. A Case Study Focusing on Tibial Plateau Fracture.

Front Bioeng Biotechnol. 2021-10-7

[6]
Evaluation of internal fixation stability of distal humerus C-type fractures based on musculoskeletal dynamics: finite element analysis under dynamic loading.

J Orthop Surg Res. 2025-5-17

[7]
[Movement analysis and musculoskeletal simulation in non-union treatment-Experiences and first clinical results].

Unfallchirurgie (Heidelb). 2022-8

[8]
Experimental and virtual testing of bone-implant systems equipped with the AO Fracture Monitor with regard to interfragmentary movement.

Front Bioeng Biotechnol. 2024-3-8

[9]
Advances in the Preoperative Planning of Revision Trauma Surgery Using 3D Printing Technology.

J Orthop Trauma. 2020-5

[10]
Different Internal Fixation Methods for Sanders Type II and III Calcaneal Fractures: A 5-Year Retrospective Study and Finite Element Analysis.

Orthop Surg. 2025-3

本文引用的文献

[1]
Individual postoperative and preoperative workflow for patients with fractures of the lower extremities.

Clin Biomech (Bristol). 2025-3-22

[2]
Experimental and virtual testing of bone-implant systems equipped with the AO Fracture Monitor with regard to interfragmentary movement.

Front Bioeng Biotechnol. 2024-3-8

[3]
Toward Digital Twin Development for Implant Placement Planning Using a Parametric Reduced-Order Model.

Bioengineering (Basel). 2024-1-16

[4]
Discrimination between the effects of pulsed electrical stimulation and electrochemically conditioned medium on human osteoblasts.

J Biol Eng. 2023-11-23

[5]
Development and validation of a digital twin of the human lower jaw under impact loading by using non-linear finite element analyses.

J Mech Behav Biomed Mater. 2023-12

[6]
Biomechanical models: key considerations in study design.

OTA Int. 2021-4-15

[7]
Application of Virtual Reality Systems in Bone Trauma Procedures.

Medicina (Kaunas). 2023-3-14

[8]
Simulation-based prediction of bone healing and treatment recommendations for lower leg fractures: Effects of motion, weight-bearing and fibular mechanics.

Front Bioeng Biotechnol. 2023-2-20

[9]
Digital twin in healthcare: Recent updates and challenges.

Digit Health. 2023-1-3

[10]
Digital Twins in Radiology.

J Clin Med. 2022-11-4

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