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1
Restoring mitochondrial function promotes hematopoietic reconstitution from cord blood following cryopreservation-related functional decline.恢复线粒体功能可促进冷冻保存相关功能衰退后脐带血的造血重建。
J Clin Invest. 2025 Mar 4;135(9). doi: 10.1172/JCI183607. eCollection 2025 May 1.
2
Long-Term Stability of Cord Blood Units After 29 Years of Cryopreservation: Follow-Up Data From the José Carreras Cord Blood Bank.29 年深低温冻存后脐血库冻存单位的长期稳定性：来自何塞·卡雷拉斯脐血库的随访数据。
Stem Cells Transl Med. 2024 Jan 12;13(1):30-42. doi: 10.1093/stcltm/szad071.
3
Insights into highly engraftable hematopoietic cells from 27-year cryopreserved umbilical cord blood.从 27 年深低温冻存的脐带血中获得具有高植入能力的造血细胞的见解。
Cell Rep Med. 2023 Nov 21;4(11):101259. doi: 10.1016/j.xcrm.2023.101259. Epub 2023 Oct 31.
4
Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study.Omidubicel 与标准清髓性脐带血移植的比较：一项 3 期随机研究结果。
Blood. 2021 Oct 21;138(16):1429-1440. doi: 10.1182/blood.2021011719.
5
Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells.靶向细胞因子检查点增强了装甲脐血 CAR-NK 细胞的适应性。
Blood. 2021 Feb 4;137(5):624-636. doi: 10.1182/blood.2020007748.
6
Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors.嵌合抗原受体修饰的自然杀伤细胞在 CD19 阳性淋巴肿瘤中的应用。
N Engl J Med. 2020 Feb 6;382(6):545-553. doi: 10.1056/NEJMoa1910607.
7
Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.使用单一UM171扩增脐血的造血干细胞移植：一项单臂1-2期安全性和可行性研究。
Lancet Haematol. 2020 Feb;7(2):e134-e145. doi: 10.1016/S2352-3026(19)30202-9. Epub 2019 Nov 6.
8
Cord-Blood Transplantation in Patients with Minimal Residual Disease.微小残留病患者的脐血移植
N Engl J Med. 2016 Sep 8;375(10):944-53. doi: 10.1056/NEJMoa1602074.
9
Impact of long-term cryopreservation on single umbilical cord blood transplantation outcomes.长期冷冻保存对单份脐血移植结果的影响。
Biol Blood Marrow Transplant. 2015 Jan;21(1):50-4. doi: 10.1016/j.bbmt.2014.09.002. Epub 2014 Sep 28.
10
Comparative single-institute analysis of cord blood transplantation from unrelated donors with bone marrow or peripheral blood stem-cell transplants from related donors in adult patients with hematologic malignancies after myeloablative conditioning regimen.清髓性预处理方案后，对成年血液系统恶性肿瘤患者进行无关供者脐血移植与相关供者骨髓或外周血干细胞移植的单机构比较分析。
Blood. 2007 Feb 1;109(3):1322-30. doi: 10.1182/blood-2006-04-020172. Epub 2006 Oct 12.

HSC "aging" of cord blood during cryopreservation and new strategy for prevention.

作者信息

Takahashi Satoshi

机构信息

Division of Clinical Precision Research Platform, Department of Hematology/Oncology, Adult Hematopoietic Cell Transplant and Cellular Immunotherapy Program, The Institute of Medical Science, The University of Tokyo, 6-1, Shirokanedai-4, Minato-ku, Tokyo 108-8639, Japan.

出版信息

Blood Sci. 2025 Jun 5;7(2):e00238. doi: 10.1097/BS9.0000000000000238. eCollection 2025 Jun.

DOI:10.1097/BS9.0000000000000238
PMID:40487191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12144646/
Abstract
摘要