Zeng Yunmin, Muhammad Abid, Wan Lingyun, Gao Chenlu, Zhao Pinyao, El-Sappah Ahmed H
Faculty of Quality Management and Inspection & Quarantine, Yibin University, Yibin, Sichuan, China.
Key Laboratory of Treatment for Special Wastewater of Sichuan Province Higher Education System, College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, China.
Front Plant Sci. 2025 May 23;16:1538664. doi: 10.3389/fpls.2025.1538664. eCollection 2025.
Climate change significantly impedes agricultural growth, development, and production. Plants adapt to environmental changes via the plasticity given by essential genes, which are regulated at the post-/transcriptional level. Gene regulation in plants is a complex process governed by various cellular entities, including transcription factors, epigenetic regulators, and non-coding RNAs. Successful studies have confirmed the function of epigenetic alterations such as DNA methylation/histone modification) in gene expression. In recent years, a highly specialized science known as "Epitranscriptomics" has emerged. Epitranscriptomics studies post-transcriptional RNA chemical alterations seen in all living organisms that alter RNA's structural, functional, and biological properties. Our minireview interpreted about understanding the molecular pathways: RNA changes and stress-responsive gene regulation. Additionally, the interplay between epitranscriptomics and other regulatory levels has been addressed. In addition, we reviewed technical breakthroughs in epitranscriptomic research, including tools and techniques.
气候变化严重阻碍了农业的增长、发展和生产。植物通过关键基因赋予的可塑性来适应环境变化，这些基因在转录后/转录水平受到调控。植物中的基因调控是一个复杂的过程，由各种细胞实体控制，包括转录因子、表观遗传调节因子和非编码RNA。成功的研究已经证实了表观遗传改变（如DNA甲基化/组蛋白修饰）在基因表达中的作用。近年来，一门名为“表观转录组学”的高度专业化科学应运而生。表观转录组学研究在所有生物体中观察到的转录后RNA化学改变，这些改变会改变RNA的结构、功能和生物学特性。我们的小型综述阐述了对分子途径的理解：RNA变化和应激反应基因调控。此外，还探讨了表观转录组学与其他调控水平之间的相互作用。此外，我们还回顾了表观转录组学研究中的技术突破，包括工具和技术。
