• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Psychoactive Plant Database: a phytochemical resource for neurological drug discovery.

作者信息

Kaur Harjot, Gupta Monika, Ahmed Zabeer, Nargotra Amit

机构信息

Discovery Informatics, NPMC Division, CSIR-Indian Institute of Integrative Medicine, Jammu, India.

Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.

出版信息

Front Pharmacol. 2025 May 23;16:1569127. doi: 10.3389/fphar.2025.1569127. eCollection 2025.

DOI:10.3389/fphar.2025.1569127
PMID:40487401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12142401/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d7b/12142401/d504583fb68f/fphar-16-1569127-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d7b/12142401/86809e3698b7/fphar-16-1569127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d7b/12142401/d504583fb68f/fphar-16-1569127-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d7b/12142401/86809e3698b7/fphar-16-1569127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d7b/12142401/d504583fb68f/fphar-16-1569127-g002.jpg

相似文献

1
Psychoactive Plant Database: a phytochemical resource for neurological drug discovery.精神活性植物数据库：用于神经药物发现的植物化学资源。
Front Pharmacol. 2025 May 23;16:1569127. doi: 10.3389/fphar.2025.1569127. eCollection 2025.
2
Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease.靶向小胶质细胞 NLRP3 炎性体及其在帕金森病中的作用。
Mov Disord. 2020 Jan;35(1):20-33. doi: 10.1002/mds.27874. Epub 2019 Nov 4.
3
Genetic and Epigenetic Regulation of the Innate Immune Response to Gout.痛风先天免疫反应的遗传和表观遗传调控。
Immunol Invest. 2023 Apr;52(3):364-397. doi: 10.1080/08820139.2023.2168554. Epub 2023 Feb 6.
4
Qingchi San treats ulcerative colitis in mice by inhibiting the nuclear factor-kappa B signaling pathway and Nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain-containing 3 inflammasome formation.清肠三方通过抑制核因子-κB 信号通路和核苷酸结合寡聚化结构域、富含亮氨酸重复和 pyrin 结构域包含 3 炎症小体的形成来治疗溃疡性结肠炎。
J Tradit Chin Med. 2023 Feb;43(1):68-77. doi: 10.19852/j.cnki.jtcm.20220928.001.
5
Nucleotide-binding domain, leucine-rich repeat, and pyrin domain-containing protein 3 inflammasome: From action mechanism to therapeutic target in clinical trials.含核苷酸结合结构域、富含亮氨酸重复序列和吡啉结构域蛋白3炎性小体：从作用机制到临床试验中的治疗靶点
World J Gastrointest Oncol. 2025 Feb 15;17(2):100094. doi: 10.4251/wjgo.v17.i2.100094.
6
Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains.前沿：卡特彼勒（CATERPILLER）：一个包含CARD、吡啉、核苷酸结合和富含亮氨酸重复结构域的哺乳动物基因大家族。
J Immunol. 2002 Oct 15;169(8):4088-93. doi: 10.4049/jimmunol.169.8.4088.
7
Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung Disease.含核苷酸结合结构域富含亮氨酸重复序列受体、含吡啉结构域的3炎性小体在肺部疾病中的调控与功能
Am J Respir Cell Mol Biol. 2016 Feb;54(2):151-60. doi: 10.1165/rcmb.2015-0231TR.
8
Apelin inhibits the activation of the nucleotide-binding domain and the leucine-rich, repeat-containing family, pyrin-containing 3 (NLRP3) inflammasome and ameliorates insulin resistance in severely burned rats.阿片肽抑制核苷酸结合结构域和富含亮氨酸重复序列家族含pyrin结构域3（NLRP3）炎性小体的激活，并改善严重烧伤大鼠的胰岛素抵抗。
Surgery. 2015 Jun;157(6):1142-52. doi: 10.1016/j.surg.2015.01.011. Epub 2015 Mar 25.
9
Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes.前沿：Monarch-1：一种控制经典和非经典MHC I类基因的吡啉/核苷酸结合域/富含亮氨酸重复序列蛋白。
J Immunol. 2003 Jun 1;170(11):5354-8. doi: 10.4049/jimmunol.170.11.5354.
10
Activation of autophagy and nucleotide-binding domain leucine-rich repeat-containing-like receptor family, pyrin domain-containing 3 inflammasome during Leishmania infantum-associated glomerulonephritis.婴儿利什曼原虫相关性肾小球肾炎期间自噬及含核苷酸结合寡聚化结构域样受体家族吡啉结构域蛋白3炎性小体的激活
Am J Pathol. 2015 Aug;185(8):2105-17. doi: 10.1016/j.ajpath.2015.04.017. Epub 2015 Jun 13.

本文引用的文献

1
Plants' Impact on the Human Brain-Exploring the Neuroprotective and Neurotoxic Potential of Plants.植物对人类大脑的影响——探索植物的神经保护和神经毒性潜力
Pharmaceuticals (Basel). 2024 Oct 7;17(10):1339. doi: 10.3390/ph17101339.
2
Combinations of (Gaertn.) Roxb. and Retz. Extracts with Selected Antibiotics Against Antibiotic-Resistant Bacteria: Bioactivity and Phytochemistry.（Gaertn.）Roxb. 和 Retz. 的提取物与选定抗生素联合对抗耐药细菌：生物活性与植物化学。
Antibiotics (Basel). 2024 Oct 19;13(10):994. doi: 10.3390/antibiotics13100994.
3
Natural Products Have Increased Rates of Clinical Trial Success throughout the Drug Development Process.
天然产物在整个药物研发过程中提高了临床试验成功率。
J Nat Prod. 2024 Jul 26;87(7):1844-1851. doi: 10.1021/acs.jnatprod.4c00581. Epub 2024 Jul 6.
4
The Use of Compounds Derived from in the Treatment of Epilepsy, Painful Conditions, and Neuropsychiatric and Neurodegenerative Disorders.在癫痫、疼痛病症以及神经精神和神经退行性疾病的治疗中使用来源于 的化合物。
Int J Mol Sci. 2024 May 25;25(11):5749. doi: 10.3390/ijms25115749.
5
Phytochemicals derived from L. plant contribute to pharmaceutical development.从L.植物中提取的植物化学物质有助于药物研发。
Front Pharmacol. 2024 Apr 12;15:1372456. doi: 10.3389/fphar.2024.1372456. eCollection 2024.
6
[Not Available].[无可用内容]
Alzheimers Dement (N Y). 2024 Apr 24;10(2):e12465. doi: 10.1002/trc2.12465. eCollection 2024 Apr-Jun.
7
Alkaloids as drug leads in Alzheimer's treatment: Mechanistic and therapeutic insights.生物碱作为阿尔茨海默病治疗的药物先导：作用机制和治疗见解。
Brain Res. 2024 Jul 1;1834:148886. doi: 10.1016/j.brainres.2024.148886. Epub 2024 Apr 4.
8
Discovery of potential WEE1 inhibitors via hybrid virtual screening.通过混合虚拟筛选发现潜在的WEE1抑制剂。
Front Pharmacol. 2023 Dec 7;14:1298245. doi: 10.3389/fphar.2023.1298245. eCollection 2023.
9
Exploring the known chemical space of the plant kingdom: insights into taxonomic patterns, knowledge gaps, and bioactive regions.探索植物王国的已知化学空间：洞察分类模式、知识空白和生物活性区域。
J Cheminform. 2023 Nov 10;15(1):107. doi: 10.1186/s13321-023-00778-w.
10
IMPPAT 2.0: An Enhanced and Expanded Phytochemical Atlas of Indian Medicinal Plants.IMPPAT 2.0：印度药用植物增强版与扩展版植物化学图谱。
ACS Omega. 2023 Feb 23;8(9):8827-8845. doi: 10.1021/acsomega.3c00156. eCollection 2023 Mar 7.