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视神经脊髓炎谱系障碍治疗的研究热点与新兴主题:文献计量分析的见解

Research hotspots and emerging topics in neuromyelitis optica spectrum disorder treatment: Insights from a bibliometric analysis.

作者信息

Wang Juan, Cai Guangbiao, Xia Shuang, Qin Jie, Liu Ben

机构信息

Department of Pediatrics, Yancheng Maternal and Child Health Care Hospital Affiliated to Yangzhou University, Yancheng, China.

Department of Orthopedics, Nantong University Medical College, Nantong, China.

出版信息

Medicine (Baltimore). 2025 Jun 6;104(23):e42850. doi: 10.1097/MD.0000000000042850.

Abstract

OBJECT

Effective treatment of neuromyelitis optica spectrum disorder (NMOSD) can greatly reduce the rate of disability and mortality among patients. NMOSD treatment studies are gaining prominence in academic circles. This study aims to depict the evolution and integration of NMOSD treatment over the past 20 years, identify key contributors in the field, clarify current research hotspots, and explore emerging topics that may guide future research directions.

METHOD

Articles in this field from 2004 to 2023 were collected from the Web of Science Core Collection (WoSCC). After conducting a literature search, a comprehensive bibliometric and knowledge mapping analysis was carried out on the retrieved articles using tools such as VOSviewer, Bibliometrix, and CiteSpace.

RESULT

The rapid growth in annual publications in this field indicates rapid progress and innovation. USA, Mayo Clinic, and Fujihara K led in productivity and impact, while the multiple sclerosis and related disorders topped in publication volume. The research hotspots in this field mainly focus on targeted biological agents. Additionally, this study has identified 3 emerging themes and conducted an in-depth exploration of their future development trends.

CONCLUSION

In summary, this bibliometric analysis provides for the first time a comprehensive framework and frontier hot spot analysis in the field of NMOSD treatment, offering references for researchers in the field and contributing to the further development of the field.

摘要

目的

有效治疗视神经脊髓炎谱系障碍(NMOSD)可大幅降低患者的致残率和死亡率。NMOSD治疗研究在学术界正日益受到关注。本研究旨在描述过去20年中NMOSD治疗的演变与整合情况,确定该领域的关键贡献者,阐明当前的研究热点,并探索可能指导未来研究方向的新出现主题。

方法

从科学网核心合集(WoSCC)收集2004年至2023年该领域的文章。在进行文献检索后,使用VOSviewer、Bibliometrix和CiteSpace等工具对检索到的文章进行全面的文献计量学和知识图谱分析。

结果

该领域年出版物数量的快速增长表明进展迅速且创新不断。美国、梅奥诊所和藤原健在生产力和影响力方面领先,而多发性硬化症及相关疾病的出版物数量最多。该领域的研究热点主要集中在靶向生物制剂。此外,本研究确定了3个新出现的主题,并对其未来发展趋势进行了深入探讨。

结论

总之,这项文献计量学分析首次提供了NMOSD治疗领域的全面框架和前沿热点分析,为该领域的研究人员提供了参考,并有助于该领域的进一步发展。

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