Kim Tark, Moehring Rebekah W, Ashley Elizabeth Dodds, Kim Hyung-Sook, Anderson Deverick J
Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
Duke Center for Antimicrobial Stewardship and Infection Prevention, Durham, NC, USA.
Infect Chemother. 2025 Jun;57(2):185-193. doi: 10.3947/ic.2024.0135. Epub 2025 Apr 28.
Given the global threat of antimicrobial-resistant organisms, an effective antimicrobial stewardship program (ASP) is essential. Infectious disease (ID) physicians and ID-trained pharmacists are prioritized as critical core members of ASP in hospital settings, but securing these ID-trained professionals in all settings is challenging. Alternative champions and personnel for implementation may be needed. This narrative review highlights the efficacy of ASP when non-ID-trained physicians and pharmacists are engaged in ASP, showcasing various studies demonstrating significant improvements in antimicrobial utilization, cost, and patient outcomes. Additionally, it discusses the impact of network-based models, such as the Duke Antimicrobial Stewardship Outreach Network, which provides structured support and resources to lower-resourced hospitals to ensure the successful implementation of ASP. Ultimately, this narrative review provides insights into how to structure accountability and pharmacy/stewardship expertise in establishing and expanding ASP nationwide in Korea, where ASP is still in its early stages. In addressing this issue, government initiatives to actively support this effort are essential, and striving to develop evidence-based policies is necessary.
鉴于抗菌耐药生物带来的全球威胁，有效的抗菌药物管理计划（ASP）至关重要。在医院环境中，传染病（ID）医生和经过ID培训的药剂师被优先视为ASP的关键核心成员，但在所有环境中确保有这些经过ID培训的专业人员具有挑战性。可能需要其他倡导者和实施人员。这篇叙述性综述强调了非ID培训的医生和药剂师参与ASP时ASP的有效性，展示了各种表明抗菌药物使用、成本和患者结局有显著改善的研究。此外，它还讨论了基于网络的模式的影响，如杜克抗菌药物管理外展网络，该网络为资源较少的医院提供结构化支持和资源，以确保ASP的成功实施。最终，这篇叙述性综述提供了关于如何在韩国全国范围内建立和扩大ASP时构建问责制以及药学/管理专业知识的见解，在韩国，ASP仍处于早期阶段。在解决这个问题时，政府积极支持这项工作的举措至关重要，努力制定基于证据的政策也是必要的。
