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[马身上一种不良药物相互作用？香豆素衍生物与苯基布他松给药期间可能出现的并发症]

[An undesirable drug interaction in horses? Complications which can occur during the administration of coumarin derivatives and phenylbutazone].

作者信息

van Miert A S

出版信息

Tijdschr Diergeneeskd. 1985 Aug 15;110(15-16):596-601.

PMID:4049359
Abstract

A study of the literature was done because of questions asked in a court of justice concerning possible poisoning in a jumper, resulting from administration of both phenylbutazone and a coumarin derivative within a particular period. In view of the mechanisms of action and the pharmacokinetic characteristics of the agents, these forms of combined treatment are also highly inadvisable in horses.

摘要

由于一家法院就一匹赛马在特定时期内同时服用保泰松和一种香豆素衍生物可能导致中毒的问题提出疑问，因此对相关文献进行了研究。鉴于这些药物的作用机制和药代动力学特征，这种联合治疗方式在马匹中也是极不可取的。

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1
[An undesirable drug interaction in horses? Complications which can occur during the administration of coumarin derivatives and phenylbutazone].[马身上一种不良药物相互作用？香豆素衍生物与苯基布他松给药期间可能出现的并发症]
Tijdschr Diergeneeskd. 1985 Aug 15;110(15-16):596-601.
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