高强度脉冲超声对姐妹染色单体交换及体外中国仓鼠卵巢细胞活力的影响缺乏效应。

Lack of effect of high-intensity pulsed ultrasound on sister chromatid exchange and in vitro Chinese hamster ovary cell viability.

作者信息

Ciaravino V, Miller M W, Carstensen E L, Dalecki D

出版信息

Ultrasound Med Biol. 1985 May-Jun;11(3):491-5. doi: 10.1016/0301-5629(85)90161-9.

Abstract

The frequency of sister chromatid exchanges (SCEs) in in vitro Chinese hamster ovary cells and their viability were not affected by 3-min exposures to 2-4 MHz, focused, pulsed ultrasound with a pulse repetition rate of 200 Hz, pulse duration of 10 mu sec and intensities (SPTP) of 500 W/cm2 and 2500 W/cm2. The viability results are consistent with those reported elsewhere; the SCE response does not verify a specific previously reported positive response.

摘要

体外培养的中国仓鼠卵巢细胞中姐妹染色单体交换（SCEs）的频率及其活力，在暴露于频率为2 - 4兆赫兹、聚焦、脉冲重复频率为200赫兹、脉冲持续时间为10微秒、空间峰值时间平均声强（SPTP）分别为500瓦/平方厘米和2500瓦/平方厘米的脉冲超声3分钟后，并未受到影响。活力结果与其他地方报道的一致；SCE反应并未证实之前报道的特定阳性反应。