Pöthig D, Ries W
Z Alternsforsch. 1985 Jul-Aug;40(4):235-44.
The authors report on first experimentally verified findings concerning the sex-specific ageing dynamism of man. The study is based on reference values of biological age which could be gathered by employing a clinical complex technique. This technique is conspicuous for its high precision; the reference-value quality of the model curves likewise satisfying all test theoretical criteria. The reference values of biological age characterize the dynamism of ageing within a randomized population group, i.e. 197 male and 168 female citizens aged between 18 and 75 years who were living in urban Leipzig and mainly employed in the working process. Remarkably enough, there hardly appear to be any differences between the two sexes as far as the rate of ageing is concerned. This causes the authors to emphasize the great importance of sex-differentiated morbidity for an increased mortality among men in the industrialized countries. A genetically predetermined higher rate of ageing among men and a resulting lower life expectancy exclusively contingent on it does not seem to exist. These experimentally obtained results correspond in tendency to epidemiological data.
作者报告了关于男性性别特异性衰老动态变化的首个经实验验证的发现。该研究基于通过采用一种临床综合技术收集的生物学年龄参考值。这项技术以其高精度而引人注目;模型曲线的参考值质量同样满足所有测试理论标准。生物学年龄参考值表征了随机人群组内的衰老动态变化,即197名年龄在18至75岁之间、居住在莱比锡市且主要从事工作的男性公民和168名女性公民。值得注意的是,就衰老速度而言,两性之间似乎几乎没有任何差异。这使得作者强调性别差异发病率对于工业化国家男性死亡率上升的重要性。似乎不存在由基因预先决定的男性更高的衰老速度以及仅由此导致的更低预期寿命。这些通过实验获得的结果在趋势上与流行病学数据相符。