Almeida Verena Calmon, Pereira Luana Caroline Dantas, da Silva Carolaine Alves, da Silva Junior Walderi Monteiro, Maciel Leonardo Yung Dos Santos, de Farias Neto Jader Pereira, de Santana Filho Valter Joviniano
Universidade Federal de Sergipe, Aracaju, Brazil.
Research Center in Physical Activity, Health and Leisure, Faculdade de desporto, universidade do porto, Portugal.
Eur Spine J. 2025 Jun 11. doi: 10.1007/s00586-025-08984-w.
Chronic low back pain may be related to central sensitization, leading to a worse prognosis for patients. Physical functioning tests allow the evaluation of the patient's daily activity. Thus, this study aims to identify the correlations between central sensitization inventory and physical functioning tests.
214 patients clinically diagnosed with chronic low back pain and reporting pain intensity above three in the numerical rate scale were included. All patients concluded the central sensitization inventory. Physical function was evaluated with the six-minute walking test (6MWT), time-up-and-go test (TUG), and one-minute sit-to-stand test (STST). The statistical analysis considered all patients and separated them by sex.
Most patients included were women, with an average age of 50 years and pain intensity considered moderate. The correlations were significant, being inverse for the 6MWT (r= -0.19, p = 0.003) and STST (r= -0.3, p < 0.001) and direct for the TUG (r = 0.20, p = 0.002). Analysing confounding factors, STST, age, pain intensity and duration and expectation have showed to significantly impact on risk of central sensitization.
The central sensitization inventory has a weak or very wear correlation with physical functioning tests.
慢性下腰痛可能与中枢敏化有关，这会导致患者预后更差。身体功能测试有助于评估患者的日常活动。因此，本研究旨在确定中枢敏化量表与身体功能测试之间的相关性。
纳入214例临床诊断为慢性下腰痛且数字评分量表疼痛强度高于3的患者。所有患者均完成了中枢敏化量表评估。采用6分钟步行试验（6MWT）、起立行走试验（TUG）和1分钟坐立试验（STST）评估身体功能。统计分析涵盖所有患者，并按性别进行分组。
纳入的患者多数为女性，平均年龄50岁，疼痛强度为中度。相关性显著，6MWT呈负相关（r = -0.19，p = 0.003），STST呈负相关（r = -0.3，p < 0.001），TUG呈正相关（r = 0.20，p = 0.002）。分析混杂因素发现，STST、年龄、疼痛强度和持续时间以及期望对中枢敏化风险有显著影响。
中枢敏化量表与身体功能测试之间的相关性较弱或非常微弱。
