Okada Hideki, Yamamori Akira, Kawazoe Naoki, Ueno Keiji, Onodera Shuichi
1 General Institute of Ohtakakohso Co., Ltd.
2 Department of Food Sciences and Human Wellness, Rakuno Gakuen University.
J Appl Glycosci (1999). 2025 May 20;72(2):7202202. doi: 10.5458/jag.7202202. eCollection 2025.
Super Ohtaka, a fermented beverage of plant extracts, is prepared from approximately 50 kinds of vegetables and fruits is a naturally fermented mainly by lactic acid bacteria ( spp.) and yeast ( spp.). In this study, we separated water-soluble polysaccharides from Super Ohtaka using dialysis and chromatography, yielding four polysaccharide fractions. The polysaccharide fraction designated as OEP3 exhibited hyaluronidase inhibitory activity. The half-maximal inhibitory concentration was 860 µg/mL. This polysaccharide not only stimulated macrophages but also inhibited hyaluronidase activity and showed weak 1,1-diphenyl-2-picrylhydrazyl radical-scavenging activity.
超级大高（Super Ohtaka）是一种植物提取物发酵饮料，由约50种蔬菜和水果制成，主要通过乳酸菌（spp.）和酵母（spp.）自然发酵而成。在本研究中，我们使用透析和色谱法从超级大高（Super Ohtaka）中分离出水溶性多糖，得到了四个多糖组分。命名为OEP3的多糖组分表现出透明质酸酶抑制活性。半数最大抑制浓度为860μg/mL。这种多糖不仅能刺激巨噬细胞，还能抑制透明质酸酶活性，并表现出较弱的1,1-二苯基-2-苦基肼自由基清除活性。
