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喉切除术后咽皮肤瘘的全厚皮片移植和胸大肌肌皮瓣修复

Reconstruction of the Pharyngocutaneous Fistula After Laryngectomy with Full-Thickness Skin Graft and Pectoralis Major Myocutaneous Flap.

作者信息

Mehel Dursun Mehmet, Cihan Seda Nur, Balaban Furkan, Yılmaz Esra, Arslan Hande, Ünal Asude

机构信息

Samsun Training and Research Hospital Otorhinolaryngology Department, University of Health Sciences, Samsun, Turkey.

Department of Otorhinolaryngology, Medical School, Samsun University, Samsun, Turkey.

出版信息

Indian J Otolaryngol Head Neck Surg. 2025 Jul;77(7):2607-2611. doi: 10.1007/s12070-025-05491-8. Epub 2025 May 20.

Abstract

Pharyngocutaneous fistula is the most common complication after total laryngectomy and increases morbidity by prolonging hospital stay. Factors such as history of radiotherapy, tumor size, anemia and diabetes are effective in its development. Treatment options include conservative and surgical methods. A 72-year-old man underwent total laryngectomy and right neck dissection for advanced laryngeal cancer. Pharyngocutaneous fistula developed on postoperative day 5. Initially, local intervention and nasogastric feeding were performed, but the defect progressed. On postoperative day 30, repair was performed with a pectoralis major myocutaneous flap. The fistula recurred because the patient did not follow the recommendations. Subsequently, a successful reconstruction was achieved with supraclavicular full-thickness skin graft and deltopectoral flap. Pharyngocutaneous fistula is a common and difficult to manage complication after total laryngectomy. Early detection and appropriate treatment approach reduces morbidity. For reconstruction of large defects, myocutaneous flaps and double-layer repair with full- thickness skin grafting are effective. In this case, the fistula was completely healed with a successful reconstruction and the patient was able to switch to oral feeding.

摘要

咽皮肤瘘是全喉切除术后最常见的并发症,会因延长住院时间而增加发病率。放疗史、肿瘤大小、贫血和糖尿病等因素对其发生有影响。治疗选择包括保守治疗和手术方法。一名72岁男性因晚期喉癌接受了全喉切除术和右侧颈部清扫术。术后第5天出现咽皮肤瘘。最初,进行了局部干预和鼻饲,但缺损仍进展。术后第30天,采用胸大肌肌皮瓣进行修复。由于患者未遵循建议,瘘复发。随后,采用锁骨上全厚皮片和三角胸皮瓣成功重建。咽皮肤瘘是全喉切除术后常见且难以处理的并发症。早期发现和适当的治疗方法可降低发病率。对于大缺损的重建,肌皮瓣和全厚皮片双层修复有效。在本例中,瘘通过成功重建完全愈合,患者能够转为经口进食。

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本文引用的文献

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A review of pharyngocutaneous fistula management in head and neck malignancies.头颈部恶性肿瘤咽皮瘘管理的综述。
Ann Palliat Med. 2023 Sep;12(5):1081-1088. doi: 10.21037/apm-22-1475. Epub 2023 Sep 7.
6
[Current treatment of pharyngocutaneous fistula after total laryngectomy].[全喉切除术后咽皮肤瘘的当前治疗方法]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Dec 5;31(23):1858-1862. doi: 10.13201/j.issn.1001-1781.2017.23.020.

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