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食管闭锁胸腔镜开放修复术的临床挑战与结果:一项单中心回顾性对照研究

Clinical challenges and outcomes of thoracoscopic open repair in esophageal atresia: a single-center retrospective comparative study.

作者信息

Ko Dayoung, Lee Ji-Hyun, Youn Joong Kee, Kim Hyun-Young

机构信息

Department of Pediatric Surgery, Seoul National University Children's Hospital, Seoul, Korea.

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.

出版信息

Ann Surg Treat Res. 2025 Jun;108(6):390-396. doi: 10.4174/astr.2025.108.6.390. Epub 2025 Jun 2.

Abstract

PURPOSE

This study aimed to compare clinical outcomes between thoracoscopic surgery (TR) and open surgery (OR) for esophageal atresia with distal tracheoesophageal fistula (EA with distal TEF) and to evaluate the feasibility of TR.

METHODS

We retrospectively analyzed the clinical data of 42 patients who underwent primary surgery for EA with distal TEF from January 2012 to December 2020. We compared the OR and TR groups based on patient characteristics, intraoperative outcomes, and early and late postoperative outcomes.

RESULTS

The TR group had longer operation times and a higher risk for intraoperative hypoxic events. Anastomosis leakage and stricture tended to occur more frequently in the TR group, although not statistically significant. The TR group required a significantly higher number of esophageal balloon dilatations (P = 0.006).

CONCLUSION

Successful TR for EA with distal TEF requires advanced anesthesia and efforts to overcome the learning curve of surgical skill with limited thoracoscopic instruments for neonates. Despite challenges, TR is considered a feasible method for EA with distal TEF patients when performed by experienced pediatric surgeons with appropriate anesthesia support.

摘要

目的

本研究旨在比较胸腔镜手术(TR)与开放手术(OR)治疗食管闭锁合并远端气管食管瘘(EA合并远端TEF)的临床疗效,并评估TR的可行性。

方法

我们回顾性分析了2012年1月至2020年12月期间接受EA合并远端TEF一期手术的42例患者的临床资料。我们根据患者特征、术中结果以及术后早期和晚期结果对OR组和TR组进行了比较。

结果

TR组手术时间更长,术中发生缺氧事件的风险更高。TR组吻合口漏和狭窄的发生率往往更高,尽管差异无统计学意义。TR组需要进行食管球囊扩张的次数显著更多(P = 0.006)。

结论

对于EA合并远端TEF成功实施TR需要先进的麻醉技术,并努力克服使用有限的新生儿胸腔镜器械进行手术操作的学习曲线。尽管存在挑战,但由经验丰富的小儿外科医生在适当的麻醉支持下进行手术时,TR被认为是治疗EA合并远端TEF患者的一种可行方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6337/12149988/78d7c78e2d68/astr-108-390-g001.jpg

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