Marén N, Calissendorff B M
Acta Ophthalmol (Copenh). 1985 Aug;63(4):415-7. doi: 10.1111/j.1755-3768.1985.tb01555.x.
The concentration of timolol in aqueous humour after one single drop of timolol ophthalmic solution was studied in 19 patients. Relatively high concentrations were found (mean: 626 ng/ml), but the individual differences were great (range: 0 ng/ml - 2080 ng/ml). Possible explanations are discussed. No detectable levels of timolol were found in plasma (detection level greater than or equal to 1 ng/ml).
对19名患者使用一滴噻吗洛尔滴眼液后房水中噻吗洛尔的浓度进行了研究。发现浓度相对较高（平均：626纳克/毫升），但个体差异很大（范围：0纳克/毫升 - 2080纳克/毫升）。讨论了可能的解释。血浆中未检测到噻吗洛尔水平（检测水平大于或等于1纳克/毫升）。
