Blanksma L J
Department of Ophthalmology, University of Groningen, The Netherlands.
Doc Ophthalmol. 1991;78(3-4):255-8. doi: 10.1007/BF00165688.
Two groups of twenty patients who were to undergo a routine e.c.c.e. applied eye-drops containing timolol 0.1% or 0.5% twice daily during the week preceding their operation. A third group of twenty patients, using placebo drops, served as control. During the cataract surgery a sample of aqueous was collected. The samples from the timolol 0.1% patient group contained a significantly lower concentration of timolol than those from the timolol 0.5% patient group, but there was considerable overlap.
两组各20名即将接受常规白内障囊外摘除术的患者，在手术前一周每天两次使用含0.1%或0.5%噻吗洛尔的眼药水。第三组20名患者使用安慰剂眼药水作为对照。在白内障手术期间采集房水样本。来自0.1%噻吗洛尔患者组的样本中噻吗洛尔浓度明显低于0.5%噻吗洛尔患者组的样本，但有相当大的重叠。
