Bilgic Omer M, Kemer Ozlem E
Bilkent City Hospital, University of Health Sciences, Ankara, Turkey.
Int Ophthalmol. 2025 Jun 12;45(1):245. doi: 10.1007/s10792-025-03616-0.
This study aims to quantify the residual ophthalmic viscosurgical device (OVD) behind the intraocular lens (IOL) following cataract surgery and evaluate its impact on intraocular pressure (IOP) and refractive changes during the postoperative period. Additionally, it examines OVD regression and associated risk factors.
Prospective Clinical Trial.
Thirty eyes of thirty patients who underwent uncomplicated cataract surgery with monofocal posterior chamber IOL implantation were included. Postoperative assessments were conducted on days 1, 3, 5, 7, 10, and 14. Using anterior segment OCT, OVD thickness behind the IOL was measured, and correlations were analyzed between OVD reduction, IOP (via non-contact tonometry), and refractive error changes. Risk factors examined included age, gender, laterality, pseudoexfoliation (psx), surgeon experience, cataract hardness, biometric data, and phacoemulsification parameters.
On day 1, mean OVD thickness was 215.7 ± 92.7 µm. A significant decrease in OVD was noted with each follow-up, with complete resorption by day 10 (p = 0.01). Initial IOP was 18.0 ± 3.3 mmHg, showing a notable reduction over time (p = 0.01). A positive correlation was observed between OVD reduction and IOP decrease from days 1 to 3 (p = 0.01, r = 0.581) and days 1 to 5 (p = 0.017, r = 0.432). Additionally, a significant association was found between OVD reduction and myopic shift from days 3 to 5 (p = 0.014, r = 0.444). Patients with thinner lenses had higher residual OVD on day 1 (p = 0.01, r = - 0.504).
Residual OVD behind the IOL may elevate IOP and cause refractive changes, emphasizing the need for thorough OVD removal and close postoperative monitoring, especially in patients with thinner lenses.
本研究旨在量化白内障手术后人工晶状体(IOL)后方残留的眼科粘弹剂(OVD),并评估其对术后眼压(IOP)和屈光变化的影响。此外,还研究了OVD的消退情况及相关危险因素。
前瞻性临床试验。
纳入30例接受单纯白内障手术并植入单焦点后房型IOL的患者的30只眼。在术后第1、3、5、7、10和14天进行评估。使用眼前节光学相干断层扫描(OCT)测量IOL后方OVD的厚度,并分析OVD减少量、IOP(通过非接触眼压计测量)和屈光不正变化之间的相关性。研究的危险因素包括年龄、性别、眼别、假性剥脱(psx)、手术医生经验、白内障硬度、生物测量数据和超声乳化参数。
术后第1天,OVD平均厚度为215.7±92.7μm。每次随访时均发现OVD有显著减少,至第10天完全吸收(p = 0.01)。初始眼压为18.0±3.3mmHg,随时间显著降低(p = 0.01)。在术后第1至3天(p = 0.01,r = 0.581)和第1至5天(p = 0.017,r = 0.432),观察到OVD减少与眼压降低之间呈正相关。此外,在术后第3至5天,发现OVD减少与近视偏移之间存在显著关联(p = 0.014,r = 0.444)。晶状体较薄的患者在术后第1天残留的OVD较高(p = 0.01,r = -0.504)。
IOL后方残留的OVD可能会升高眼压并引起屈光变化,强调需要彻底清除OVD并进行密切的术后监测,尤其是对于晶状体较薄的患者。