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与静脉注射去铁胺相关的血小板减少症。

Thrombocytopenia associated with intravenous desferrioxamine.

作者信息

Walker J A, Sherman R A, Eisinger R P

出版信息

Am J Kidney Dis. 1985 Oct;6(4):254-6. doi: 10.1016/s0272-6386(85)80183-9.

DOI:10.1016/s0272-6386(85)80183-9
PMID:4050784
Abstract

Desferrioxamine (DFO) was administered intravenously to a 63-year-old chronic hemodialysis patient with osteomalacia believed secondary to aluminum intoxication. Thrombocytopenia was noted after five doses of DFO. Platelet counts normalized after DFO was withheld. Thrombocytopenia recurred upon two rechallenges with this drug. It is suggested that platelet counts be monitored in hemodialysis patients receiving intravenous DFO.

摘要

去铁胺(DFO)静脉注射给了一名63岁的患有骨软化症的慢性血液透析患者,该骨软化症被认为继发于铝中毒。在给予五剂DFO后发现血小板减少。停用DFO后血小板计数恢复正常。再次使用该药物两次后血小板减少复发。建议对接受静脉注射DFO的血液透析患者监测血小板计数。

相似文献

1
Thrombocytopenia associated with intravenous desferrioxamine.与静脉注射去铁胺相关的血小板减少症。
Am J Kidney Dis. 1985 Oct;6(4):254-6. doi: 10.1016/s0272-6386(85)80183-9.
2
Clearance of aluminum by hemodialysis: effect of desferrioxamine.血液透析对铝的清除:去铁胺的作用
Kidney Int Suppl. 1986 Feb;18:S100-3.
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Desferrioxamine in the treatment of aluminum overload.去铁胺治疗铝过载。
Clin Nephrol. 1985;24 Suppl 1:S94-7.
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Precipitation of dialysis dementia by deferoxamine treatment of aluminum-related bone disease.用去铁胺治疗铝相关性骨病引发透析性痴呆
Am J Kidney Dis. 1988 Aug;12(2):126-30. doi: 10.1016/s0272-6386(88)80007-6.
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[Desferrioxamine treatment of osteomalacia caused by aluminum poisoning].[去铁胺治疗铝中毒所致骨软化症]
Presse Med. 1986 Jan 18;15(2):55-9.
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Changes in bone histology after treatment with desferrioxamine.去铁胺治疗后骨组织学的变化。
Kidney Int Suppl. 1986 Feb;18:S108-13.
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Indirect methods for the diagnosis of aluminum bone disease: plasma aluminum, the desferrioxamine infusion test, and serum iPTH.铝骨病的间接诊断方法:血浆铝、去铁胺输注试验和血清iPTH。
Kidney Int Suppl. 1986 Feb;18:S96-9.
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Desferrioxamine therapy in hemodialysis patients with aluminum-associated bone disease.
Kidney Int. 1989 Jun;35(6):1371-8. doi: 10.1038/ki.1989.136.
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Aluminum intoxication of bone in renal failure--fact or fiction?
Kidney Int Suppl. 1986 Feb;18:S70-3.
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The role of desferrioxamine in dialysis-associated mucormycosis: report of three cases and review of the literature.去铁胺在透析相关毛霉菌病中的作用:三例报告及文献复习
Clin Nephrol. 1988 May;29(5):261-6.

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