Ługowski Franciszek, Babińska Julia, Kwiatkowski Jakub, Akpang Nicole, Urban Aleksandra, Kacperczyk-Bartnik Joanna, Bartnik Paweł, Dobrowolska-Redo Agnieszka, Romejko-Wolniewicz Ewa, Sieńko Jacek
2nd Department of Obstetrics and Gynecology, Medical University of Warsaw, Karowa 2 Street, 00-315 Warsaw, Poland.
Healthcare (Basel). 2025 May 29;13(11):1290. doi: 10.3390/healthcare13111290.
Influenza is an acute viral disease that primarily affects the airways. It is caused by influenza A and B-RNA viruses. The disease is associated with significant morbidity and mortality. The prevention of influenza includes chemoprophylaxis and vaccination, which are the primary preventive measures against influenza infection and should be highly considered by everyone during influenza season. A systematic literature search was performed in the databases of PubMed, Web of Science, Scopus, and Embase until September 2024. The review was conducted following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Eventually, a total of 20 publications were included in the final analysis of this systematic review. While general awareness of influenza was moderate, detailed understanding of complications and vaccine safety was frequently lacking. Misconceptions-such as fears of fetal harm and confusion between antiviral and antibiotic treatments-were widespread. Vaccine uptake was generally low but strongly correlated with receiving a healthcare provider recommendation. Willingness to vaccinate was higher in settings where participants were educated during the study process, indicating a crucial role of health communication. According to the reviewed literature, the reluctance to receive maternal vaccination often stems primarily from fears or concerns about adverse reactions or misconceptions about the vaccine's effectiveness, as well as the absence of a physician's recommendation. Misconceptions regarding vaccine safety, limited understanding of influenza severity, and a lack of clear communication from healthcare professionals are key contributors to low vaccination uptake. Importantly, multiple studies confirmed that recommendation by a trusted healthcare provider significantly increases vaccine acceptance. These findings highlight the urgent need for targeted educational strategies, improved antenatal counseling, and systems-level support to ensure that maternal influenza vaccination becomes a standard and trusted component of prenatal care worldwide.
流感是一种主要影响气道的急性病毒性疾病。它由甲型和乙型流感RNA病毒引起。该疾病与显著的发病率和死亡率相关。流感的预防包括化学预防和接种疫苗，这是预防流感感染的主要措施，在流感季节每个人都应高度重视。截至2024年9月，在PubMed、科学网、Scopus和Embase数据库中进行了系统的文献检索。该综述按照系统评价和荟萃分析的首选报告项目（PRISMA）指南进行。最终，共有20篇出版物纳入了本系统评价的最终分析。虽然对流感的总体认识一般，但对并发症和疫苗安全性的详细了解常常缺乏。诸如担心对胎儿有害以及对抗病毒治疗和抗生素治疗的混淆等误解很普遍。疫苗接种率总体较低，但与接受医疗保健提供者的建议密切相关。在研究过程中对参与者进行教育的环境中，接种意愿较高，这表明健康沟通起着关键作用。根据综述文献，不愿接受孕产妇疫苗接种通常主要源于对不良反应的恐惧或担忧、对疫苗有效性的误解，以及缺乏医生的建议。对疫苗安全性的误解、对流感严重程度的了解有限以及医疗保健专业人员缺乏明确的沟通是疫苗接种率低的关键因素。重要的是，多项研究证实，值得信赖的医疗保健提供者的建议会显著提高疫苗的接受度。这些发现凸显了迫切需要有针对性的教育策略、改善产前咨询以及系统层面的支持，以确保孕产妇流感疫苗接种成为全球产前护理的标准且值得信赖的组成部分。
