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本文引用的文献

1
Organ preservation after neoadjuvant long-course chemoradiotherapy versus short-course radiotherapy.新辅助长程放化疗后与短程放疗的器官保存。
Ann Oncol. 2024 Nov;35(11):1003-1014. doi: 10.1016/j.annonc.2024.07.729. Epub 2024 Sep 11.
2
Early-Onset colorectal Cancer: From the laboratory to the clinic.早发性结直肠癌：从实验室到临床。
Cancer Treat Rev. 2024 Nov;130:102821. doi: 10.1016/j.ctrv.2024.102821. Epub 2024 Aug 30.
3
Effect of neoadjuvant chemoradiotherapy with or without PD-1 antibody sintilimab in pMMR locally advanced rectal cancer: A randomized clinical trial.新辅助放化疗联合或不联合 PD-1 抗体信迪利单抗治疗错配修复蛋白阳性局部晚期直肠癌的随机临床试验
Cancer Cell. 2024 Sep 9;42(9):1570-1581.e4. doi: 10.1016/j.ccell.2024.07.004. Epub 2024 Aug 1.
4
Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial.mFOLFIRINOX 新辅助治疗与术前放化疗对比局部进展期直肠癌的疗效：UNICANCER-PRODIGE 23 临床试验的长期结果。
Ann Oncol. 2024 Oct;35(10):873-881. doi: 10.1016/j.annonc.2024.06.019. Epub 2024 Jul 8.
5
Comment on: "Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial".对《FOWARC试验中，新辅助化疗对于早期局部晚期直肠癌并不劣于放化疗》的评论
Br J Cancer. 2024 May;130(9):1432-1433. doi: 10.1038/s41416-024-02690-y. Epub 2024 Apr 22.
6
Future direction of total neoadjuvant therapy for locally advanced rectal cancer.局部进展期直肠癌新辅助治疗的未来方向。
Nat Rev Gastroenterol Hepatol. 2024 Jun;21(6):444-455. doi: 10.1038/s41575-024-00900-9. Epub 2024 Mar 14.
7
Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial.在 FOWARC 试验中，新辅助化疗对于早发性局部进展期直肠癌不劣于放化疗。
Br J Cancer. 2024 May;130(9):1434-1440. doi: 10.1038/s41416-024-02652-4. Epub 2024 Mar 12.
8
Long-Term Results of Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy: The Randomized Phase II OPRA Trial.总新辅助治疗直肠腺癌患者的器官保存的长期结果：随机 II 期 OPRA 试验。
J Clin Oncol. 2024 Feb 10;42(5):500-506. doi: 10.1200/JCO.23.01208. Epub 2023 Oct 26.
9
Dynamic circulating tumor DNA during chemoradiotherapy predicts clinical outcomes for locally advanced non-small cell lung cancer patients.动态循环肿瘤 DNA 在放化疗期间可预测局部晚期非小细胞肺癌患者的临床结局。
Cancer Cell. 2023 Oct 9;41(10):1763-1773.e4. doi: 10.1016/j.ccell.2023.09.007.
10
Preoperative Treatment of Locally Advanced Rectal Cancer.局部进展期直肠癌的术前治疗。
N Engl J Med. 2023 Jul 27;389(4):322-334. doi: 10.1056/NEJMoa2303269. Epub 2023 Jun 4.

Lessons from FOWARC: moving towards the more precise use of radiation therapy in the era of total neoadjuvant therapy.

作者信息

Bercz Aron, Zambare Wini, Smith J Joshua

机构信息

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Department of Surgery, Colorectal Service, New York, NY, USA.

出版信息

AME Clin Trials Rev. 2025 Apr 25;3. doi: 10.21037/actr-24-219. Epub 2025 Mar 21.

DOI:10.21037/actr-24-219
PMID:40511302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12159757/
Abstract
摘要