Zhang Yu, Li Fengrui, Yan Honglei, Zhang Yan, Feng Shimiao, Deng Lei, Zhao Lixia, Gao Shuang, Fu Ying, Ye Fei
Department of Chemistry, Northeast Agricultural University, Harbin 150030, China.
Food Chem X. 2025 May 26;28:102584. doi: 10.1016/j.fochx.2025.102584. eCollection 2025 May.
The development of bio-based active food packaging is urgently needed to address food safety concerns. In this study, nerolidol/hydroxypropyl--cyclodextrin inclusion complex nanofibers (Nerolidol/HPCD-IC-NF) were prepared by electrospinning to improve the thermal stability and water solubility of natural antimicrobial nerolidol. Structural characterization (FTIR, XRD, H NMR) confirmed successful nerolidol encapsulation within HPCD cavities. The resulting bead-free nanofibers exhibited high surface area and porosity. Nerolidol/HPCD-IC-NF demonstrated a 3.3-fold increase in free radical scavenging capacity compared to free nerolidol, along with potent antimicrobial activity (88.1 % and 76.0 % inhibition against and , respectively). In strawberry preservation trials, nanofiber membranes reduced lesion diameters by 5.56-fold after 5 days compared to untreated controls, significantly extending shelf life. These findings highlight Nerolidol/HPCD-IC-NF as a promising solution for preventing microbial contamination and improving food preservation efficacy in active packaging applications.
迫切需要开发基于生物的活性食品包装来解决食品安全问题。在本研究中，通过静电纺丝制备了橙花叔醇/羟丙基-β-环糊精包合物纳米纤维（Nerolidol/HPCD-IC-NF），以提高天然抗菌剂橙花叔醇的热稳定性和水溶性。结构表征（傅里叶变换红外光谱、X射线衍射、核磁共振氢谱）证实橙花叔醇成功包封于羟丙基-β-环糊精空腔内。所得无珠纳米纤维具有高比表面积和孔隙率。与游离橙花叔醇相比，Nerolidol/HPCD-IC-NF的自由基清除能力提高了3.3倍，同时具有强大的抗菌活性（对大肠杆菌和金黄色葡萄球菌的抑制率分别为88.1%和76.0%）。在草莓保鲜试验中，与未处理的对照相比，纳米纤维膜在5天后使损伤直径减小了5.56倍，显著延长了货架期。这些发现突出了Nerolidol/HPCD-IC-NF作为一种有前景的解决方案，可用于在活性包装应用中防止微生物污染并提高食品保鲜效果。
