Sensitive dual detection of N-nitrosodiphenylamine and N-nitrosodiethylamine using a PtNPs-enhanced MWCNTs/Fe-porphyrinic MOF nanocomposite-based electrochemical sensor.

N-nitrosamines, such as N-nitrosodiphenylamine (NDPhA) and N-nitrosodiethylamine (NDEA), are potent carcinogens frequently detected in food and water, posing significant health risks. This study presents a novel non-enzymatic electrochemical sensor using platinum nanoparticles (PtNPs) electrodeposited on a composite of multi-walled carbon nanotubes (MWCNTs)/iron-porphyrinic metal-organic framework (MOF) PCN-600 nanocomposite for the sensitive and simultaneous detection of NDPhA and NDEA. The nanocomposite was synthesized via a solvothermal method, MWCNTs in the nanocomposite prevented MOF aggregation and enhanced conductivity. The sensor achieved linear ranges of 0.08-10.0 μg mL for NDPhA and 1.5-350.0 μg mL for NDEA, with detection limits of 6.534 × 10 μg mL and 0.173 μg mL, respectively. It exhibited high stability (92.6 % current retention after 30 days), reproducibility, and specificity, with recovery rates in spiked tap water and tobacco sample. This approach offers a rapid, and on-site applicable cost-effective alternative method for N-nitrosamine detection, promoting food safety and environmental surveillance.