Han Yu, Li Xin, Liu Yan, Zhao Jing, Gao Yuqi, Li Xiaotong, Wang Fengdan, Zhu Ying, Xin Sitong, Li Bo, Liu Zhigang
Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, China.
Quality Control Office, Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
J Cardiol. 2025 Jun 14. doi: 10.1016/j.jjcc.2025.06.005.
Cardiometabolic multimorbidity (CMM) is defined as the coexistence of two or more cardiometabolic diseases, including hypertension, diabetes, stroke, and cardiovascular disease. Weekend catch-up sleep (WCS) is an effective repayment of sleep debt, and the association between WCS and CMM, and between WCS and CMM under the influence of average sleep duration, weekday sleep duration, and weekend sleep duration is unknown. The aim of this study was to determine the association between WCS and CMM and their association under different sleep durations.
A cross-sectional study was conducted using the 2017-2018 US National Health and Nutrition Examination Survey dataset (N = 3431). Weighted multivariate logistic regression models estimated the odds ratio (OR) and their 95 % confidence interval (95%CI) between WCS and CMM, associations between WCS and CMM under different sleep duration stratifications were examined. A restricted cubic spline plot was used to describe the relationship between various sleep durations, WCS durations, and the prevalence of CMM.
WCS made a statistically significant difference between those with CMM and no-CMM (p < 0.001). After adjusting for covariates, WCS was found to be a protective factor for CMM with OR of 0.531 (0.360, 0.784). After stratified analyses with different sleep durations, it was found that WCS remained a protective factor for CMM in those with different sleep durations <8 h.
There was an association between WCS and CMM. WCS was a protective factor for CMM. WCS remained a protective factor for CMM across different sleep durations <8 h.
心脏代谢性多种疾病（CMM）被定义为两种或更多种心脏代谢性疾病同时存在，包括高血压、糖尿病、中风和心血管疾病。周末补觉（WCS）是对睡眠债的有效偿还，WCS与CMM之间的关联，以及在平均睡眠时间、工作日睡眠时间和周末睡眠时间影响下WCS与CMM之间的关联尚不清楚。本研究的目的是确定WCS与CMM之间的关联以及它们在不同睡眠时间下的关联。
使用2017 - 2018年美国国家健康和营养检查调查数据集（N = 3431）进行横断面研究。加权多变量逻辑回归模型估计WCS与CMM之间的比值比（OR）及其95%置信区间（95%CI），并检验不同睡眠时间分层下WCS与CMM之间的关联。使用受限立方样条图来描述各种睡眠时间、WCS时长与CMM患病率之间的关系。
WCS在患有CMM和未患有CMM的人群之间存在统计学显著差异（p < 0.001）。在调整协变量后，发现WCS是CMM的保护因素，OR为0.531（0.360，0.784）。在按不同睡眠时间进行分层分析后，发现在睡眠时间<8小时的不同人群中，WCS仍然是CMM的保护因素。
WCS与CMM之间存在关联。WCS是CMM的保护因素。在睡眠时间<8小时的不同人群中，WCS仍然是CMM的保护因素。
