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深圳引入超声引导高强度聚焦超声(USgHIFU)前后子宫腺肌病的治疗策略

Treatment strategies for adenomyosis before and after introducing USgHIFU in Shenzhen.

作者信息

Dai Yu, Luo Huang-Jin, Peng Yan, Yang Weichun, Shi Qiuling, Jin Ping

机构信息

Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, China.

Women and Children's Medical Center, Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, China.

出版信息

Int J Hyperthermia. 2025 Dec;42(1):2501244. doi: 10.1080/02656736.2025.2501244. Epub 2025 Jun 16.

DOI:10.1080/02656736.2025.2501244
PMID:40518987
Abstract

OBJECTIVE

To explore the impact of ultrasound-guided high-intensity focused ultrasound (USgHIFU) on patients with adenomyosis in Shenzhen and the changes in health economics.

DESIGN

A retrospective observational study.

SETTING

Hospitals.

PATIENTS

1093 patients with adenomyosis either treated with surgery or USgHIFU.

INTERVENTION(S): Surgical treatment and USgHIFU.

MAIN OUTCOME MEASURE(S): Demographic information on the patients including age, education, marital status, job, fertility requirement and clinical characteristics such as fertility history, dysmenorrhea, degree of dysmenorrhea, hypermenorrhea, duration of dysmenorrhea, Numerical Rating Scale and history of cesarean section were recorded.

RESULTS

The overall trend in the number of patients with adenomyois was increasing after introduction. The average hospital stay of USgHIFU was decreasing year by year, and it was lowest among the three groups with below the total average length of hospitalization. The average cost of patients treated with USgHIFU was decreasing with the total earing for the hospital increasing. Compared to those with USgHIFU, patients selected hysterectomy are older (odds ratio [OR] = 1.17, 95% confidence interval [CI]: 1.13-1.21). However, patients undergoing hysterectomy have fewer symptoms of dysmenorrhea (OR = 0.31, 95% CI: 0.80-1.42) and tend to have lower educational levels. Patients selected adenomyomectomy tended to experience lower levels of dysmenorrhea (OR = 0.76, 95% CI: 0.60-0.93.

CONCLUSION(S): USgHIFU reduces the cost and length of hospitalization for patients with adenomyosis and increases hospital revenue from these patients. It provides a suitable option for women with who have a strong desire to retain their uterus.

摘要

目的

探讨超声引导下高强度聚焦超声(USgHIFU)对深圳子宫腺肌病患者的影响以及卫生经济学的变化。

设计

一项回顾性观察研究。

地点

医院。

患者

1093例接受手术或USgHIFU治疗的子宫腺肌病患者。

干预措施

手术治疗和USgHIFU。

主要观察指标

记录患者的人口统计学信息,包括年龄、教育程度、婚姻状况、职业、生育需求,以及生育史、痛经、痛经程度、月经过多、痛经持续时间、数字评分量表和剖宫产史等临床特征。

结果

引入后子宫腺肌病患者数量总体呈上升趋势。USgHIFU组的平均住院天数逐年下降,在三组中最短,低于总平均住院时长。接受USgHIFU治疗的患者平均费用随着医院总收入的增加而降低。与接受USgHIFU治疗的患者相比,选择子宫切除术的患者年龄更大(优势比[OR]=1.17,95%置信区间[CI]:1.13 - 1.21)。然而,接受子宫切除术的患者痛经症状较少(OR = 0.31,95% CI:0.80 - 1.42),且教育水平往往较低。选择腺肌病切除术的患者痛经程度往往较低(OR = 0.76,95% CI:0.60 - 0.93)。

结论

USgHIFU降低了子宫腺肌病患者的费用和住院时长,并增加了医院从这些患者身上获得的收入。它为强烈希望保留子宫的女性提供了一个合适的选择。

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