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伊朗胃肠道癌症幸存者的生活质量及预测因素

Quality of Life and Predictors among Gastrointestinal Cancer Survivors in Iran.

作者信息

Ghaderi Musab, Shamsi Afzal, Azadi Arman, Rahmani Azad

机构信息

Instructor, Department of Nursing, Khalkhal University of Medical Sciences, Khalkhal, Iran.

Faculty Allied Medicine, Tehran University of Medical Science, Tehran, Iran.

出版信息

Iran J Nurs Midwifery Res. 2025 May 8;30(3):343-348. doi: 10.4103/ijnmr.ijnmr_93_23. eCollection 2025 May-Jun.

Abstract

BACKGROUND

Quality of life (QoL) is an important indicator for evaluating treatment outcomes among cancer patients. Therefore, this study aimed to assess QoL and associated factors among Iranian gastric and colorectal cancer survivors.

MATERIALS AND METHODS

This epidemiologic study was conducted among 120 gastric and colorectal cancer survivors in Shahid Ghazi Hospital affiliated to Tabriz University of Medical Sciences, Iran, in 2019. Participants were selected through the convenience sampling method. The data collection instrument included a demographic and disease-related checklist and cancer-related QoL questionnaire (QLQ-C30). Data were collected using face-to-face interviews and analyzed by the logistic regression model.

RESULTS

The average overall QoL score was 48.98. Based on the threshold, more than half of the participants had a problem in physical performance, cognitive performance, emotional performance, fatigue, pain, and financial subscales. Anemia and marital status were the most predictors in all subscales. HTN and physical activity are the strongest predictors for global QoL subscale and symptom subscale, respectively. These factors predicted a significant proportion of variance for QoL (84% for global QoL, 83.50% for functional subscale, and 67.30% for symptom subscale).

CONCLUSIONS

Our findings highlighted that the QoL level of gastrointestinal cancer patients was low. In our study, anemia, marital status, BUN/Cr, HTN, and physical activity were identified as the most important predictor factors of QoL. Therefore, it seems that the formulation and implementation of supportive care programs that aimed to resolve these health problems can play a crucial role in improving the QoL of patients.

摘要

背景

生活质量(QoL)是评估癌症患者治疗效果的重要指标。因此,本研究旨在评估伊朗胃癌和结直肠癌幸存者的生活质量及其相关因素。

材料与方法

2019年,在伊朗大不里士医科大学附属沙希德·加齐医院对120名胃癌和结直肠癌幸存者进行了这项流行病学研究。参与者通过便利抽样法选取。数据收集工具包括一份人口统计学和疾病相关清单以及癌症相关生活质量问卷(QLQ-C30)。通过面对面访谈收集数据,并采用逻辑回归模型进行分析。

结果

总体生活质量平均得分为48.98。根据阈值,超过一半的参与者在身体功能、认知功能、情绪功能、疲劳、疼痛和财务分量表方面存在问题。贫血和婚姻状况是所有分量表中最主要的预测因素。高血压和身体活动分别是总体生活质量分量表和症状分量表的最强预测因素。这些因素预测了生活质量的很大一部分变异(总体生活质量为84%,功能分量表为83.50%,症状分量表为67.30%)。

结论

我们的研究结果突出表明胃肠道癌症患者的生活质量水平较低。在我们的研究中,贫血、婚姻状况、血尿素氮/肌酐、高血压和身体活动被确定为生活质量的最重要预测因素。因此,制定和实施旨在解决这些健康问题的支持性护理计划似乎可以在改善患者生活质量方面发挥关键作用。

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