Bener Abdulbari, Alsulaiman Reem, Doodson Lisa, El Ayoubi Hanadi R
Department of Biostatistics and Medical Informatics, Cerrahpaşa Faculty of Medicine, Istanbul University, İstanbul, Turkey, Turkey.
Department of Evidence for Population Health Unit, School of Epidemiology and Health Sciences, University of Manchester, Manchester, UK.
J Family Med Prim Care. 2017 Oct-Dec;6(4):824-831. doi: 10.4103/jfmpc.jfmpc_17_17.
Breast cancer has been the most common cancer type that affects women worldwide and subsequent treatment is often associated with considerable psychological and quality of life (QoL).
This study aimed to assess psychometric properties of the Arabic version of the European Organization for Research and Treatment of Cancer (EORTC) general QoL questionnaire (QLQ-C30) for breast cancer patients in Qatar.
This is a cross-sectional hospital-based study conducted on 678 breast cancer patients using Arabic version of the EORTC QLQ-C30 tool.
The mean age of women was 47.7 ± 10.2 years and 33.4% of women had consanguineous parents. Six subscales out of the nine met the standards of reliability with coefficients ranging from 0.55 to 0.89. The mean score of all functioning scales was high >55. Advanced breast cancer stages of III-IV had higher symptomatic scores significantly than those in early stages for the physical function, cognitive, fatigue, insomnia, appetite loss, constipation, and financial difficulties. Correlation coefficients between each item ranged from -0.113 to 0.960, and item 21 (tense) and item 23 (irritable) had strongest negative correlations with their corresponding emotional functioning subscale, whereas items 29 (physical condition) and 30 (overall QoL) had the strongest positive correlation with Global Health/QoL subscale. Item 6 (limited work) showed a higher correlation with fatigue ( = 0.749). Likewise, item 19 (pain interfered with daily activities) of the pain subscale had higher correlations with physical functioning, role functioning, and fatigue subscales.
Qatari Arabic version of the EORTC QLQ-C30 showed acceptable psychometric properties, which is a reliable and valid instrument, that can be used by oncologists.
乳腺癌一直是全球影响女性的最常见癌症类型，后续治疗通常会对心理和生活质量（QoL）产生重大影响。
本研究旨在评估欧洲癌症研究与治疗组织（EORTC）通用生活质量问卷（QLQ-C30）阿拉伯语版用于卡塔尔乳腺癌患者的心理测量特性。
这是一项基于医院的横断面研究，对678例乳腺癌患者使用EORTC QLQ-C30工具的阿拉伯语版进行研究。
女性的平均年龄为47.7±10.2岁，33.4%的女性父母为近亲。九个分量表中的六个符合可靠性标准，系数范围为0.55至0.89。所有功能量表的平均得分都很高，>55。III-IV期晚期乳腺癌患者在身体功能、认知、疲劳、失眠、食欲减退、便秘和经济困难方面的症状得分明显高于早期患者。各项目之间的相关系数范围为-0.113至0.960，项目21（紧张）和项目23（易怒）与其相应的情绪功能分量表的负相关性最强，而项目29（身体状况）和项目30（总体生活质量）与全球健康/生活质量分量表的正相关性最强。项目6（工作受限）与疲劳的相关性较高（=0.749）。同样，疼痛分量表中的项目19（疼痛干扰日常活动）与身体功能、角色功能和疲劳分量表的相关性较高。
EORTC QLQ-C30的卡塔尔阿拉伯语版显示出可接受的心理测量特性，是一种可靠有效的工具可供肿瘤学家使用。
