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1987年至2021年毛里求斯心血管疾病(定义为心电图异常和/或自我报告事件)患病率趋势:对七项大型基于人群的调查数据的分析

Trends in the prevalence of cardiovascular disease, defined as ECG abnormalities and/or self-reported events, in Mauritius between 1987 and 2021: analysis of data from seven large population-based surveys.

作者信息

Söderberg Stefan, Taki Hina, Kowlessur Sudhir, Shaw Jonathan E, Magliano Dianna J, Tamosiunas Abdonas, Alberti George, Zimmet Paul, Tuomilehto Jaakko

机构信息

Department of Public Health and Clinical Medicine, Umeå University, Umea, Sweden

Department of Public Health and Clinical Medicine, Umeå University, Umea, Sweden.

出版信息

BMJ Open. 2025 Jun 16;15(6):e087693. doi: 10.1136/bmjopen-2024-087693.

Abstract

OBJECTIVE

To estimate the prevalence of coronary heart disease (CHD) in Mauritius. Over the last half century, rapid socioeconomic development has taken place in the multiethnic Mauritius. It is unclear if this is paralleled with an increasing prevalence of CHD.

DESIGN

Repeated cross-sectional population-based studies.

SETTING

Mauritius.

PARTICIPANTS

Seven population-based surveys were performed in Mauritius between 1987 and 2021. Altogether, 29 997 participants aged 35-74 years were included.

MEASURES

Except in 2004 and 2021, all participants were examined with an ECG. ECG changes were classified as 'probable CHD' and 'possible CHD' according to the Minnesota Code model. Participants were asked about previous myocardial infarction, stroke and angina pectoris as told by a doctor. An affirmative answer to any of these questions was labelled as the presence of cardiovascular disease (CVD). Since 2009, questions about previous coronary bypass surgery and percutaneous coronary intervention were included. The prevalence estimates were age and sex standardised to the 2008 Mauritian population. Multivariable logistic regression evaluated associations between traditional CVD risk factors and CHD.

RESULTS

The prevalence (with 95% CI) of probable CHD according to ECG did not increase between 1987 and 2015, 1.6% (1.2-2.1%) and 1.9% (1.5-2.3%), respectively, whereas the prevalence of possible CHD decreased, 23.7% (22.3-25.1%) and 17.3% (16.2-18.3%), respectively. Self-reported CVD did not increase between 1987 and 2021. Male sex, diabetes, impaired glucose tolerance (IGT), hypertension, smoking and self-reported history of CVD were associated independently with probable CHD, whereas female sex, IGT, hypertension, high cholesterol and self-reported history of CVD were associated independently with possible CHD. Ethnicity did not associate with probable CHD but with possible CHD. Postload plasma glucose associated with probable and possible CHD.

CONCLUSIONS

The prevalence of probable CHD according to ECG and the prevalence of self-reported history of CVD did not increase in Mauritius. Traditional cardiovascular risk factors were associated significantly with the presence of probable and possible CHD.

摘要

目的

评估毛里求斯冠心病(CHD)的患病率。在过去的半个世纪里,多民族的毛里求斯经历了快速的社会经济发展。目前尚不清楚这是否与冠心病患病率的上升同步。

设计

基于人群的重复横断面研究。

地点

毛里求斯。

参与者

1987年至2021年间,在毛里求斯进行了七次基于人群的调查。总共纳入了29997名年龄在35 - 74岁之间的参与者。

测量方法

除2004年和2021年外,所有参与者均接受心电图检查。根据明尼苏达编码模型,心电图变化被分类为“可能的冠心病”和“可能的冠心病”。参与者被问及医生告知的既往心肌梗死、中风和心绞痛情况。对这些问题中的任何一个给出肯定回答都被标记为存在心血管疾病(CVD)。自2009年起,增加了关于既往冠状动脉搭桥手术和经皮冠状动脉介入治疗的问题。患病率估计值按年龄和性别标准化为2008年毛里求斯人口数据。多变量逻辑回归分析评估传统心血管疾病危险因素与冠心病之间的关联。

结果

根据心电图诊断的可能冠心病患病率(95%可信区间)在1987年至2015年期间没有增加,分别为1.6%(1.2 - 2.1%)和1.9%(1.5 - 2.3%),而可能的冠心病患病率有所下降,分别为23.7%(22.3 - 25.1%)和17.3%(16.2 - 18.3%)。自我报告的心血管疾病在1987年至2021年期间没有增加。男性、糖尿病、糖耐量受损(IGT)、高血压、吸烟和自我报告的心血管疾病史与可能的冠心病独立相关,而女性、IGT、高血压、高胆固醇和自我报告的心血管疾病史与可能的冠心病独立相关。种族与可能的冠心病无关,但与可能的冠心病有关。负荷后血糖与可能的和可能的冠心病有关。

结论

在毛里求斯,根据心电图诊断的可能冠心病患病率和自我报告的心血管疾病史患病率没有增加。传统心血管危险因素与可能的和可能的冠心病的存在显著相关。

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