Liu Linlin, Zheng Hecheng, Zou Tiantian, Li Xiangping, Huang Renwu, Qing Lili, Nie Shengjie, Hu Liping
Shanghai Key Laboratory of Forensic Medicine and Key Laboratory of Forensic Science, Ministry of Justice, Shanghai, People's Republic of China.
NHC Key Laboratory of Drug Addiction Medicine, School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan, People's Republic of China.
Ann Hum Genet. 2025 Nov;89(6):446-449. doi: 10.1111/ahg.12602. Epub 2025 Jun 16.
To study the genetic characteristics of X-chromosome short tandem repeats (X-STRs) in the Yunnan Yi ethnic minority.
We analyzed the allele frequencies and forensic parameters for 16 X-STR loci in 432 unrelated Yi individuals (206 males and 226 females) in Chuxiong Yi Autonomous Prefecture, Yunnan Province.
A total of 130 alleles were detected. Except for DXS6800, the other loci are highly polymorphic in the Yunnan Yi ethnicity. The combined values of discrimination for males (PDM) and females (PDF) were 0.999999999968561 and 0.999999999999993, respectively, which can be used for forensic medical identification and genetic studies. On the basis of the results of population comparison, there seems to be a relatively close evolutionary relationship between adjacent populations and different ethnic groups in the same region.
This study contributes to X-chromosome genetic polymorphism data for the Yunnan Yi ethnicity and further enriches reference materials on the Chinese Yi ethnic minority.
研究云南彝族X染色体短串联重复序列（X-STRs）的遗传特征。
我们分析了云南省楚雄彝族自治州432名无血缘关系的彝族个体（206名男性和226名女性）中16个X-STR基因座的等位基因频率和法医学参数。
共检测到130个等位基因。除DXS6800外，其他基因座在云南彝族中具有高度多态性。男性鉴别力（PDM）和女性鉴别力（PDF）的合并值分别为0.999999999968561和0.999999999999993，可用于法医学鉴定和遗传学研究。基于群体比较结果，相邻群体和同一地区不同民族之间似乎存在相对密切的进化关系。
本研究为云南彝族提供了X染色体遗传多态性数据，进一步丰富了中国彝族的参考资料。
