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免疫功能正常患者发生与器械相关的侵袭性感染后的脑病和眼内炎：一例报告

Encephalopathy and Endophthalmitis Following Device-Related Invasive Infection in an Immunocompetent Patient: A Case Report.

作者信息

Cui Yi, Huang Zhenxing, Han Hui, Ma Yang, Li Shanshan, Hu Yuanyuan, Zhang Hui, Zhang Xuehai, Zhao Xiuhe, Yu Dexin, Li Jianqiao, Liu Han, Li Chen, Wang Hao

机构信息

Department of Critical Care Medicine Qilu Hospital of Shandong University Jinan China.

Department of Ophthalmology Qilu Hospital of Shandong University Jinan China.

出版信息

Clin Case Rep. 2025 Jun 16;13(6):e70550. doi: 10.1002/ccr3.70550. eCollection 2025 Jun.

DOI:10.1002/ccr3.70550
PMID:40524943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12168220/
Abstract

Device-related Candida infections are becoming more prevalent, even among immunocompetent individuals. For patients diagnosed with invasive candidiasis, it is essential to perform a fundoscopic examination, irrespective of the presence of ocular symptoms. If infected implanted devices cannot be removed, individualized antifungal regimens and long-term treatment are crucial.

摘要

与器械相关的念珠菌感染正变得越来越普遍，即使在免疫功能正常的个体中也是如此。对于诊断为侵袭性念珠菌病的患者，无论是否存在眼部症状，进行眼底检查都至关重要。如果无法取出受感染的植入器械，个体化的抗真菌治疗方案和长期治疗至关重要。

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本文引用的文献

1
Invasive candidiasis.侵袭性念珠菌病。
Nat Rev Dis Primers. 2024 Mar 21;10(1):20. doi: 10.1038/s41572-024-00503-3.
2
: Biology, Pathogenicity, Virulence Factors, Diagnosis, and Treatment.生物学、致病性、毒力因子、诊断与治疗
Infect Drug Resist. 2022 Aug 31;15:5121-5135. doi: 10.2147/IDR.S383785. eCollection 2022.
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Pathogens in Vasculitis: Is It Really Idiopathic?血管炎中的病原体：真的是特发性的吗？
JMA J. 2021 Jul 15;4(3):216-224. doi: 10.31662/jmaj.2021-0021. Epub 2021 Jul 9.
4
Candidemia and Invasive Candidiasis.念珠菌血症和侵袭性念珠菌病。
Infect Dis Clin North Am. 2021 Jun;35(2):389-413. doi: 10.1016/j.idc.2021.03.007.
5
Intradural cauda equina Candida abscess presenting with hydrocephalus: case report.硬脊膜内马尾神经念珠菌脓肿伴脑积水：病例报告
J Neurosurg Spine. 2019 Aug 30;31(6):890-893. doi: 10.3171/2019.6.SPINE19271. Print 2019 Dec 1.
6
Update on fungal infections of the central nervous system: emerging pathogens and emerging diagnostics.中枢神经系统真菌感染的最新进展：新出现的病原体和新出现的诊断方法。
Curr Opin Infect Dis. 2019 Jun;32(3):277-284. doi: 10.1097/QCO.0000000000000541.
7
Neuroinfections caused by fungi.真菌感染所致的神经感染。
Infection. 2018 Aug;46(4):443-459. doi: 10.1007/s15010-018-1152-2. Epub 2018 May 21.
8
Bilateral Candida endophthalmitis accompanying Candida lusitaniae bloodstream infection: A case report.伴有葡萄牙念珠菌血流感染的双侧念珠菌性眼内炎：一例报告。
J Infect Chemother. 2018 Feb;24(2):147-149. doi: 10.1016/j.jiac.2017.10.002. Epub 2017 Oct 26.
9
Bacterial and Fungal Endophthalmitis.细菌性和真菌性眼内炎
Clin Microbiol Rev. 2017 Jul;30(3):597-613. doi: 10.1128/CMR.00113-16.
10
Meningitis Caused by Candida Dubliniensis in a Patient with Cirrhosis: A Case Report and Review of the Literature.一名肝硬化患者由都柏林念珠菌引起的脑膜炎：病例报告及文献复习
Mycopathologia. 2016 Aug;181(7-8):589-93. doi: 10.1007/s11046-016-0006-7. Epub 2016 Apr 1.