Afanas'ev Iu I, Nozdrin V I, Mikhaĭlov O I, Nikiforov S A, Volkov Iu T
Biull Eksp Biol Med. 1985 Oct;100(10):463-6.
The influence of retinyl acetate, retinoic acid and its esterified cis- and trans-derivatives, retinoids C15 and C20 on erythrocytes, liver macrophages and white pulp of the spleen was studied in the experiments on mice of different strains. It was found that administration of these compounds leads to the damage of the blood cells, increase in the number of liver macrophages and the share of white pulp in the spleen and stimulation of the local response to tuberculin. The interdependence of changes in the blood and adjuvant is suggested.
在对不同品系小鼠进行的实验中，研究了醋酸视黄酯、视黄酸及其酯化的顺式和反式衍生物、类视黄醇C15和C20对红细胞、肝巨噬细胞和脾白髓的影响。发现给予这些化合物会导致血细胞损伤、肝巨噬细胞数量增加以及脾白髓比例增加，并刺激对结核菌素的局部反应。提示血液变化与佐剂之间存在相互依存关系。
