Sabnis Ram W
Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Atlanta, Georgia 30309, United States.
ACS Med Chem Lett. 2025 May 9;16(6):927-928. doi: 10.1021/acsmedchemlett.5c00228. eCollection 2025 Jun 12.
Provided herein are novel azaindazole derivatives as HCN2 modulators, pharmaceutical compositions, use of such compounds in treating central nervous system (CNS) and psychiatric disorders, namely, schizophrenia, autism and mood disorders, and processes for preparing such compounds.
本文提供了作为HCN2调节剂的新型氮杂吲哚衍生物、药物组合物、此类化合物在治疗中枢神经系统(CNS)和精神疾病(即精神分裂症、自闭症和情绪障碍)中的用途,以及制备此类化合物的方法。