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从肯尼亚婴儿中分离出的携带碳青霉烯酶且PBP3插入的多重耐药菌的基因组特征分析

Genomic characterization of multidrug-resistant with PBP3 insertions carrying carbapenemase isolated from infants in Kenya.

作者信息

Kariuki Kevin, Kigen Collins, Wachira James, Mogeni Polycarp, Rwigi Doreen, Singa Benson, Tickell Kirkby D, Fang Ferric C, Kariuki Samuel, Walson Judd L, Pavlinac Patricia B

机构信息

Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.

Centre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.

出版信息

Microbiol Resour Announc. 2025 Jul 10;14(7):e0012125. doi: 10.1128/mra.00121-25. Epub 2025 Jun 18.

Abstract

We report on carbapenem-resistant ST46 and 167 strains isolated from fecal samples of 4- and 8-month-old infants, respectively, in Kenya, collected at discharge after more than 4 days of hospitalization. The isolates carried carbapenemase and a PBP3 (YRIN/K) insertion. This finding has implications for patient management.

摘要

我们报告了分别从肯尼亚4个月和8个月大婴儿的粪便样本中分离出的耐碳青霉烯类ST46和167菌株,这些样本是在住院超过4天后出院时采集的。分离菌株携带碳青霉烯酶和PBP3(YRIN/K)插入。这一发现对患者管理具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c9e/12243540/e94938b6ac33/mra.00121-25.f001.jpg

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