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从肯尼亚婴儿中分离出的携带碳青霉烯酶且PBP3插入的多重耐药菌的基因组特征分析

Genomic characterization of multidrug-resistant with PBP3 insertions carrying carbapenemase isolated from infants in Kenya.

作者信息

Kariuki Kevin, Kigen Collins, Wachira James, Mogeni Polycarp, Rwigi Doreen, Singa Benson, Tickell Kirkby D, Fang Ferric C, Kariuki Samuel, Walson Judd L, Pavlinac Patricia B

机构信息

Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.

Centre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.

出版信息

Microbiol Resour Announc. 2025 Jul 10;14(7):e0012125. doi: 10.1128/mra.00121-25. Epub 2025 Jun 18.

DOI:10.1128/mra.00121-25
PMID:40530867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12243540/
Abstract

We report on carbapenem-resistant ST46 and 167 strains isolated from fecal samples of 4- and 8-month-old infants, respectively, in Kenya, collected at discharge after more than 4 days of hospitalization. The isolates carried carbapenemase and a PBP3 (YRIN/K) insertion. This finding has implications for patient management.

摘要

我们报告了分别从肯尼亚4个月和8个月大婴儿的粪便样本中分离出的耐碳青霉烯类ST46和167菌株，这些样本是在住院超过4天后出院时采集的。分离菌株携带碳青霉烯酶和PBP3（YRIN/K）插入。这一发现对患者管理具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c9e/12243540/e94938b6ac33/mra.00121-25.f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c9e/12243540/e94938b6ac33/mra.00121-25.f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c9e/12243540/e94938b6ac33/mra.00121-25.f001.jpg

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本文引用的文献

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J Antimicrob Chemother. 2025 Jan 3;80(1):178-181. doi: 10.1093/jac/dkae393.
2
An NDM-Producing Clinical Isolate Exhibiting Resistance to Cefiderocol and the Combination of Ceftazidime-Avibactam and Aztreonam: Another Step Toward Pan-β-Lactam Resistance.一株产NDM的临床分离株对头孢地尔、头孢他啶-阿维巴坦合剂及氨曲南耐药：迈向泛β-内酰胺耐药的又一步。
Open Forum Infect Dis. 2023 May 17;10(7):ofad276. doi: 10.1093/ofid/ofad276. eCollection 2023 Jul.
3
Recurrent spontaneous meningitis in an adult: a case report.
一名成人复发性自发性脑膜炎：病例报告
JAC Antimicrob Resist. 2023 Mar 28;5(2):dlad029. doi: 10.1093/jacamr/dlad029. eCollection 2023 Apr.
4
Genomic transmission analysis of multidrug-resistant Gram-negative bacteria within a newborn unit of a Kenyan tertiary hospital: A four-month prospective colonization study.肯尼亚一家三级医院新生儿病房内多重耐药革兰氏阴性菌的基因组传播分析：一项为期四个月的前瞻性定植研究。
Front Cell Infect Microbiol. 2022 Aug 25;12:892126. doi: 10.3389/fcimb.2022.892126. eCollection 2022.
5
Antimicrobial resistance including Extended Spectrum Beta Lactamases (ESBL) among E. coli isolated from kenyan children at hospital discharge.肯尼亚住院儿童出院时分离的大肠杆菌中包括超广谱β-内酰胺酶（ESBL）在内的抗菌药物耐药性。
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6
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