Fu Chen-Chen, Huang Bao-Xing, Zhang Xinghao, Zhou Jian-Li, Mao Shu-Yi, Fan Tai-Ping, Zhang Jian-Hua, Wang Shan-Shan, Chen Mo-Xian, Zhu Fu-Yuan
National Key Laboratory for the Development and Utilization of Forest Food Resources, State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of State Forestry and Grassland Administration on Subtropical Forest Biodiversity Conservation, The Southern Modern Forestry Collaborative Innovation Center, College of Life Sciences, Nanjing Forestry University, Nanjing 210037, China.
Clinical Laboratory, Shenzhen Children's Hospital, Shenzhen 518000, China.
J Agric Food Chem. 2025 Jul 2;73(26):16049-16063. doi: 10.1021/acs.jafc.5c02632. Epub 2025 Jun 18.
Agarwood is a highly valued resinous wood typically formed in as a defensive response to external damage, such as external injury or stress. It has a high market economy value and can be used not only as ornamental art but also for the diagnosis and treatment of diseases. During the growth and development of , the regulation of genes and secondary metabolites is particularly important. However, research on the composition of secretions following injury remains in its early stages. This study investigates resin secretion by in response to external damage. Results revealed that secretes a large amount of 2-(2-phenethyl) chromone compounds in response to external damage. Because the chemical structures of these compounds are considerably similar to those of flavonoids, this study compares the two types of compounds from the perspectives of their metabolite chemical structures, biosynthetic pathways, triggered molecular responses, and medicinal value. The analysis of the main chemical components of agarwood and its medicinal value can serve as a foundation for the artificial cultivation of high-quality agarwood in the future.
沉香是一种极具价值的含树脂木材，通常是在对外界损伤（如外部伤害或压力）的防御反应中形成的。它具有很高的市场经济价值，不仅可以用作装饰艺术品，还可用于疾病的诊断和治疗。在沉香的生长发育过程中，基因和次生代谢产物的调控尤为重要。然而，关于沉香受伤后分泌物组成的研究仍处于早期阶段。本研究调查了沉香对外部损伤的树脂分泌情况。结果显示，沉香在受到外部损伤时会分泌大量的2-（2-苯乙基）色酮化合物。由于这些化合物的化学结构与黄酮类化合物相当相似，本研究从代谢物化学结构、生物合成途径、引发的分子反应和药用价值等方面对这两类化合物进行了比较。对沉香主要化学成分及其药用价值的分析可为未来高品质沉香的人工种植奠定基础。
