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迷幻药与睡眠的交叉研究:探索对睡眠结构、梦境状态及治疗意义的影响

The Intersection of Psychedelics and Sleep: Exploring the Impacts on Sleep Architecture, Dream States, and Therapeutic Implications.

作者信息

Zhai Haojiang, Wang Hongshuang, Li Haohong, Wang Xiaohui

机构信息

Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.

School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, China.

出版信息

ACS Pharmacol Transl Sci. 2025 May 15;8(6):1832-1836. doi: 10.1021/acsptsci.5c00234. eCollection 2025 Jun 13.

Abstract

The interplay between psychedelics, such as psilocybin, lysergic acid diethylamide (LSD) and dimethyltryptamine (DMT), and sleep is an emerging area, but their impact on sleep remains relatively underexplored. This viewpoint provides a perspective on how psychedelics may alter sleep phases, dreaming, and their potential therapeutic applications for sleep disorders.

摘要

诸如裸盖菇素、麦角酸二乙酰胺(LSD)和二甲基色胺(DMT)等迷幻剂与睡眠之间的相互作用是一个新兴领域,但它们对睡眠的影响仍相对未得到充分探索。本文观点阐述了迷幻剂可能如何改变睡眠阶段、梦境以及它们对睡眠障碍的潜在治疗应用。

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本文引用的文献

1
Preliminary Evidence of Sleep Improvements Following Psilocybin Administration, and their Involvement in Antidepressant Therapeutic Action.
Curr Psychiatry Rep. 2024 Nov;26(11):659-669. doi: 10.1007/s11920-024-01539-8. Epub 2024 Nov 13.
3
LSD increases sleep duration the night after microdosing.
Transl Psychiatry. 2024 Apr 15;14(1):191. doi: 10.1038/s41398-024-02900-4.
4
Vivid dreams are associated with a high percentage of REM sleep: a prospective study in veterans.
J Clin Sleep Med. 2023 Sep 1;19(9):1661-1668. doi: 10.5664/jcsm.10642.
5
Converging theories on dreaming: Between Freud, predictive processing, and psychedelic research.
Front Hum Neurosci. 2023 Feb 16;17:1080177. doi: 10.3389/fnhum.2023.1080177. eCollection 2023.
6
Efficacy and tolerability of pharmacological treatments for insomnia in adults: A systematic review and network meta-analysis.
Sleep Med Rev. 2023 Apr;68:101746. doi: 10.1016/j.smrv.2023.101746. Epub 2023 Jan 14.
7
The neural basis of psychedelic action.
Nat Neurosci. 2022 Nov;25(11):1407-1419. doi: 10.1038/s41593-022-01177-4. Epub 2022 Oct 24.
8
Default Mode Network Modulation by Psychedelics: A Systematic Review.
Int J Neuropsychopharmacol. 2023 Mar 22;26(3):155-188. doi: 10.1093/ijnp/pyac074.
9
Phenomenology and content of the inhaled N, N-dimethyltryptamine (N, N-DMT) experience.
Sci Rep. 2022 May 24;12(1):8562. doi: 10.1038/s41598-022-11999-8.
10
Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice.
Transl Psychiatry. 2022 Feb 23;12(1):77. doi: 10.1038/s41398-022-01846-9.

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