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迷幻药与睡眠的交叉研究:探索对睡眠结构、梦境状态及治疗意义的影响

The Intersection of Psychedelics and Sleep: Exploring the Impacts on Sleep Architecture, Dream States, and Therapeutic Implications.

作者信息

Zhai Haojiang, Wang Hongshuang, Li Haohong, Wang Xiaohui

机构信息

Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.

School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, China.

出版信息

ACS Pharmacol Transl Sci. 2025 May 15;8(6):1832-1836. doi: 10.1021/acsptsci.5c00234. eCollection 2025 Jun 13.

Abstract

The interplay between psychedelics, such as psilocybin, lysergic acid diethylamide (LSD) and dimethyltryptamine (DMT), and sleep is an emerging area, but their impact on sleep remains relatively underexplored. This viewpoint provides a perspective on how psychedelics may alter sleep phases, dreaming, and their potential therapeutic applications for sleep disorders.

摘要

诸如裸盖菇素、麦角酸二乙酰胺(LSD)和二甲基色胺(DMT)等迷幻剂与睡眠之间的相互作用是一个新兴领域,但它们对睡眠的影响仍相对未得到充分探索。本文观点阐述了迷幻剂可能如何改变睡眠阶段、梦境以及它们对睡眠障碍的潜在治疗应用。

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本文引用的文献

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The neural basis of psychedelic action.迷幻剂作用的神经基础。
Nat Neurosci. 2022 Nov;25(11):1407-1419. doi: 10.1038/s41593-022-01177-4. Epub 2022 Oct 24.

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